Fadee Mondalek

US Patent:

20140275263, Sep 18, 2014

Filed:

Mar 14, 2014

Appl. No.:

14/212675

Inventors:

- Oklahoma City OK, US
Fadee G. Mondalek - Oklahoma City OK, US
Rafal A. Farjo - Oklahoma City OK, US
Alexander B. Quiambao - Oklahoma City OK, US
Didier J. Nuño - Oklahoma City OK, US

Assignee:

EyeCRO, LLC - Oklahoma City OK

International Classification:

A61K 47/34
A61K 31/122
A61K 31/192
A61K 9/00
A61K 47/14

US Classification:

514569, 514785, 514772, 514571

Abstract:

Provided are pharmaceutical carriers suitable based on oil-in-water microemulsions and methods of making same. Also provided are pharmaceutical compositions comprising a carrier of the invention and a lipophilic active pharmaceutical ingredient (API), as well as methods for making same. The pharmaceutical compositions are particularly suitable for use in formulating lipophilic APIs for topical administration to the eye. Specifically included are pharmaceutical compositions comprising fenofibrate or fenofibric acid as API. Also provided is a method of treating a disease of the posterior segment of the eye. Also provided is a pharmaceutical composition comprising a compound represented byformulated for topical administration to the eye.