Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.
Jun 2011 to 2000 Senoir Scientist, R&D Chemistry departmentUniversity of Pittsburgh Pittsburgh, PA Jul 2007 to Jun 2011 Research Assistant Professor, Advanced Regenerative Medicine FellowUniversity of Massachusetts, Medical School Worcester, MA Jul 2007 to Jul 2007 Postdoctoral Researcher, Department of OrthopedicsNational University of Singapore Singapore Aug 2003 to Jul 2006 Postdoctoral Research Fellow, Nanoscience and Nanotechnology Initiative
Zhejiang University Hangzhou, CN 1999 to 2003 Ph.D. in Chemistry and PhysicsQingdao University of Science and Technology Qingdao, CN 1996 to 1999 M.S.Qingdao University of Science and Technology Qingdao, CN 1992 to 1996 B.S.E. in Polymer Science