Thomas A Hasling from Yorktown, VA, age 53

Method And Apparatus For Generating And Positioning Micro-Scale Evanescent Fields
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US Patent:

8451448, May 28, 2013
Filed:

Oct 16, 2009
Appl. No.:

12/589017
Inventors:

Thomas Hasling - Honolulu HI, US
Assignee:

Oceanit Laboratories, Inc. - Honolulu HI
International Classification:

G01N 21/55
US Classification:

356445
Abstract:

Illumination sources are connected to ends of micropipette probes having total internal reflection tips. The total internal reflection produces evanescence at the tips. The evanescence causes fluorescence of dye marked target molecules at tips of the probes. The evanescence is limited to about 100 nm from the tips. The presence of a target molecule at the end of a probe is observed by observing the fluorescence. The limited penetration of the evanescence eliminates noise in the signal and unwanted bleaching of dyes in the cell, so that repeated, multiple and arrays of probes may be applied.

Microscope Illumination Device And Adapter Therefor
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US Patent:

20050237605, Oct 27, 2005
Filed:

Apr 15, 2005
Appl. No.:

11/106819
Inventors:

Vitaly Vodyanoy - Auburn AL, US
Oleg Pustovyy - Auburn AL, US
Thomas Hasling - Columbus GA, US
International Classification:

G02B021/00
G02B021/06
US Classification:

359385000, 359368000
Abstract:

An illumination system for a microscope, including a light source for generating light to illuminate a sample for microscopic observation, at least one collimating lens for collimating light generated by the light source, and a darkfield condenser for receiving collimated light and directing a hollow cone of light onto the sample under observation. The system optionally includes an adapter for enhancing economy of light transmission from the light source to the specimen, the adapter having a centrally disposed spacer and a plurality of optical fibers surrounding the spacer, to generate a hollow cylinder of light for transmission to the darkfield condenser. The system provides improved resolution and contrast, and is well suited for adaptation to fluorescence microscopy techniques.

System For And Method Of Patch Clamp Analysis
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US Patent:

20060166185, Jul 27, 2006
Filed:

Jan 27, 2006
Appl. No.:

11/341160
Inventors:

Solomon Yilma - Iowa City IA, US
Charles Ellis - Auburn AL, US
Bogdan Wilamowski - Auburn AL, US
Thomas Hasling - Columbus GA, US
International Classification:

C12Q 1/00
US Classification:

435004000, 205777000
Abstract:

A system and method for automated patch clamp analysis of biological tissue such as cellular membrane. A biological membrane is applied to a porous semiconductor substrate, and laser energy is imparted thereon. Voltage clamped electrodes detect current across the membrane to indicate ion channel activity.

Translational Filter, Shutter, Aperture Apparatus For Selecting And Combining Filtered And Unfiltered Light
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US Patent:

20070242335, Oct 18, 2007
Filed:

Feb 20, 2007
Appl. No.:

11/708877
Inventors:

Thomas Hasling - Columbus GA, US
Vitaly Vodyanoy - Auburn AL, US
Oleg Pustovyy - Auburn AL, US
International Classification:

G02B 26/02
US Classification:

359230000, 359233000
Abstract:

A method and apparatus for filtering and mixing light is provided. The apparatus comprises a translational filter, aperture and shutter. A light beam and the translational filter, aperture and shutter are moved relative to each other to precisely control the proportions of filtered, unobstructed and blocked light. A method for precisely controlling the proportions of filtered, unobstructed and blocked light is also provided. Optional accessories include additional translational filters, apertures and shutters, light guides, relay lenses, microscopes, computers, motors for controlling the positions of the components, focusing lenses, and mechanical shutters.

Consumer Electronic Camera Photoplethysmograph
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US Patent:

20100268094, Oct 21, 2010
Filed:

Apr 15, 2010
Appl. No.:

12/798992
Inventors:

Thomas Hasling - Honolulu HI, US
Luke Joseph - Honolulu HI, US
Todd Blume - Honolulu HI, US
International Classification:

A61B 5/0205
US Classification:

600484
Abstract:

A body part is placed on or near a consumer electronic device camera. The camera senses periodic light variations. A program analyses variations in images captured by the digital camera to determine pulse rate or breathing rate.