Vitaly Vodyanoy - Auburn AL, US Alexandre M. Samoylov - Auburn AL, US Tatiana I. Samoylova - Auburn AL, US Suram T. Pathirana - Sunnyvale CA, US
Assignee:
Auburn University - Auburn AL
International Classification:
G01N 33/53
US Classification:
435 71, 435 72, 435 697, 436 71, 436 86, 422105
Abstract:
Methods and compositions for evaluating the affinity of one or more ligands of interest are provided. In particular, a ligand sensor device (LSD) comprising a sensor coupled to a peptide of interest is provided. Assays using the LSD allow detection of ligand-peptide interactions directly in tissue samples and thus provide an in vitro assay to characterize peptide ligands. The LSD and assays find particular use in characterizing cell-specific peptides isolated from in vivo screening in animals to determine their suitability for use in human therapy.
Use Of Acacia Gum To Isolate And Preserve A Biological Receptor On A Biosensor
Vitaly J. Vodyanoy - Auburn AL, US James M. Barbaree - Dadeville AL, US Bryan A. Chin - Auburn AL, US William Charles Neely - Auburn AL, US Suram T. Pathirana - Sunnyvale CA, US Timothy D. Braden - Auburn AL, US
Assignee:
Auburn University - Auburn AL
International Classification:
C12M 1/34 C12Q 1/68 G01N 33/53
US Classification:
4352872, 435 6, 435 71
Abstract:
Compositions and methods for the reversible preservation of biological samples are provided. The compositions include Gum, including derivations and modifications thereof which are useful as a reversible preservation solution. A method is provided for using Gum to isolate and reversibly preserve a biological specimen in a dormant state at room temperature for an extended period with minimal damage to the specimen. The compositions and methods disclosed may also be used to create reversibly preserved biological specimens and biological receptors for use in biosensors.
Use Of Pullulan To Isolate And Preserve Biological Material
Vitaly J. Vodyanoy - Auburn AL, US James M. Barbaree - Dadeville AL, US Bryan A. Chin - Auburn AL, US William Charles Neely - Auburn AL, US Suram T. Pathirana - Sunnyvale CA, US Timothy D. Braden - Auburn AL, US
Assignee:
Auburn University - Auburn AL
International Classification:
C12N 1/04 C12N 5/06 C12Q 1/68 A01N 63/02
US Classification:
42419518, 435 4, 435260
Abstract:
Compositions and methods for the reversible preservation of biological samples are provided. The compositions include natural polymers such as pullulan or acacia gum, including derivations and modifications thereof, which are usefull as a reversible preservation solution. A method is provided for using pullulan or Acacia Gum to isolate and reversibly preserve a biological specimen in a dormant state at room temperature for an extended period with minimal damage to the specimen. The compositions and methods disclosed may also be used to create reversibly preserved biological specimens and biological receptors for use in biosensors.
Use Of Acacia Gum To Isolate And Preserve Biological Material
Vitaly Vodyanoy - Auburn AL, US James Barbaree - Dadeville AL, US Bryan Chin - Auburn AL, US William Neely - Auburn AL, US Suram Pathirana - Sunnyvale CA, US Timothy Braden - Auburn AL, US
International Classification:
A61K035/78 C12N001/04 A01N065/00
US Classification:
435/260000, 424/725000
Abstract:
Compositions and methods for the reversible preservation of biological samples are provided. The compositions include Acacia Gum, including derivations and modifications thereof which are useful as a reversible preservation solution. A method is provided for using Acacia Gum to isolate and reversibly preserve a biological specimen in a dormant state at room temperature for an extended period with minimal damage to the specimen. The compositions and methods disclosed may also be used to create reversibly preserved biological specimens and biological receptors for use in biosensors.