Nantkwest
Senior Director Primary Lymphocyte R and D
Sorrento Therapeutics, Inc. Oct 2016 - Aug 2017
Senior Director Cellular Therapy - Tnk Therapeutics
Sorrento Therapeutics, Inc. Jun 2015 - Oct 2016
Director Experimental Cellular Therapy -- Tnk
Hyperstem Therapeutics Dec 2014 - Jun 2015
Vice President Stem Cell Development
Genelux 2010 - 2014
Director of Cancer Stem Cell Diagnostics and Therapy
Education:
Texas A&M University
Doctorates, Doctor of Philosophy
Skills:
Drug Discovery Biotechnology Assay Development Cancer Cell In Vitro Oncology Drug Development Pharmaceutical Industry In Vivo Life Sciences Stem Cells High Throughput Screening Molecular Biology Infectious Diseases Clinical Trials Immunology Lifesciences Virology Biopharmaceuticals Biologics Translational Medicine Elisa Cancer Biology Specializing In Cancer Stem Cell Models Cancer Biology Western Blotting Lead Change Pharmacology Protein Chemistry Glp Toxicology Biomarkers Monoclonal Antibodies Biomarker Discovery Laboratory Translational Research Drug Design Small Molecules Pharmacokinetics Purification Drug Metabolism Translationally Relevant Cancer Models Antibodies Ind
Interests:
Boating Electronics Outdoors Home Improvement Reading Sports Home Decoration
Rohit Duggal - San Diego CA, US Amy Patick - Escondido CA, US Jie Zhang - Carlsbad CA, US Weidong Zhao - San Diego CA, US
Assignee:
Agouron Pharmaceuticals, Inc.
International Classification:
C12Q001/70 C12Q001/68 C07H021/04 C12P001/00
US Classification:
435/006000, 536/023720, 435/041000
Abstract:
The invention relates to a reporter-selectable hepatitis C virus (HCV) replicon, and use of the replicon to generate stable, human hepatoma cell lines. The replicon and cell lines are useful in the compound screening process in HCV drug discovery.
Inhibitors Of Hepatitis C Virus, Compositions And Treatments Using The Same
Rohit Duggal - San Diego CA, US Koleen Herlihy - San Diego CA, US Wei Liu - San Diego CA, US Amy Patick - Escondido CA, US Eiann Sha - San Diego CA, US Weidong Hao - San Diego CA, US
Assignee:
AGOURON PHARMACEUTICALS, INC.
International Classification:
A61K038/05 A61K031/4965
US Classification:
514/018000, 514/255050
Abstract:
The invention relates to methods of inhibiting HCV viral replication activity comprising contacting an HCV polymerase with a therapeutically effective amount of a hydroxamate MMP inhibitor, and compositions comprising the same.
Dual Reporter/Dye Reduction Methodology For Evaluating Antiviral And Cytotoxicity Of Hepatitis C Virus Inhibitors
Mary Brothers - Del Mar CA, US Rohit Duggal - San Diego CA, US Koleen Herlihy - San Diego CA, US Amy Patick - Escondido CA, US Weidong Hao - San Diego CA, US
Assignee:
Agouron Pharmaceuticals, Inc.
International Classification:
C12Q001/70 C12Q001/68
US Classification:
435/005000
Abstract:
Methods are provided for evaluating the antiviral activity and cytotoxicity of a compound in the same population of cells by the use of reporter genes and dye reduction methodology. The dual antiviral activity/cytotoxicity reporter methods are amenable for use in a high-throughput format.
Disclosed herein are recombinant nucleic acids, comprising a 5′ untranslated (5′-UTR) sequence portion, a signal peptide sequence portion, a single chain antibody fragment sequence portion, a hinge region sequence portion, a transmembrane domain sequence portion, and one or more intracellular domain sequence portions. Also disclosed herein are modified natural killer (NK) cells comprising the recombinant nucleic acid described above. Further disclosed herein are methods of treating a tumor in a subject by administering the modified NK cells.
News
Stephen Lawrence murder: inside the violent, racist world of gang led by self ...
In July 1992 an Asian boy, Rohit Duggal, was stabbed to death by Peter Thompson, again on Well Hall Road. Thompson was named as a member of the Acourts gang in the anonymous calls to the police the day after Stephens death.