Rebeca B Geffin

US Patent:

20110027313, Feb 3, 2011

Filed:

Apr 6, 2009

Appl. No.:

12/936165

Inventors:

Rebeca Geffin - North Miami Beach FL, US
Richard Myers - Miami Beach FL, US

Assignee:

University Of Miami - Miami Beach FL

International Classification:

A61K 39/12
C12N 15/74
C12N 7/01
C40B 40/02
A61P 31/12

US Classification:

4242051, 435477, 4352351, 506 14

Abstract:

The invention uses recombinant technology to create infectious molecular clones that capture the sequence diversity of viral genes found in natural populations of mixed genotype viruses, such as arises during HIV infections and many other viral diseases. The invention captures the sequence diversity of different genes in these “quasi-species” populations by recombining them into in a constant genetic “backbone” for each viral species by backcrossing PCR products derived from quasispecies gene variants into this backbone in an BAC plasmid.

Address:

19430 NE 21 Ct, Miami, FL 33179

VIN:

2T1BR32E17C837610

Make:

TOYOTA

Model:

COROLLA

Year:

2007