Ray Vanderby

US Patent:

7744535, Jun 29, 2010

Filed:

Oct 16, 2006

Appl. No.:

11/549865

Inventors:

Ray Vanderby - Madison WI, US
Hirohito Kobayashi - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600438, 600437, 600442, 600443, 600448, 310311

Abstract:

An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.

US Patent:

7776815, Aug 17, 2010

Filed:

Feb 23, 2005

Appl. No.:

11/063627

Inventors:

Ray Vanderby - Madison WI, US
Kelley Dwyer Grorud - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61K 38/00
C07K 2/00

US Classification:

514 2, 530300

Abstract:

Disclosed are a method and a corresponding pharmaceutical composition for treating damaged ligaments. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of ligaments damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).

US Patent:

7928059, Apr 19, 2011

Filed:

May 10, 2006

Appl. No.:

11/431347

Inventors:

Ray Vanderby - Madison WI, US
Kelley W. Grorud - Janesville WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61K 38/00
A61K 35/30
A61K 35/32
A61K 35/12
C07K 14/00

US Classification:

514 2, 530350, 530839, 530840, 424548, 424570, 424520

Abstract:

Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of cartilage and bone damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).

US Patent:

8282553, Oct 9, 2012

Filed:

May 18, 2010

Appl. No.:

12/782068

Inventors:

Ray Vanderby - Madison WI, US
Hirohito Kobayashi - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600437, 600407, 600438, 600442, 600443

Abstract:

An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.

US Patent:

8332166, Dec 11, 2012

Filed:

May 5, 2010

Appl. No.:

12/774387

Inventors:

Ray Vanderby - Madison WI, US
Hirohito Kobayashi - Madison WI, US

International Classification:

G06F 19/00
A61B 8/00

US Classification:

702 42, 600438

Abstract:

An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.

US Patent:

20050074800, Apr 7, 2005

Filed:

Aug 30, 2004

Appl. No.:

10/929919

Inventors:

Peter Muir - Madison WI, US
Ray Vanderby - Madison WI, US
Paolo Provenzano - Madison WI, US

International Classification:

C12Q001/68
C12Q001/37

US Classification:

435006000, 435023000

Abstract:

Disclosed are methods for detecting and treating joint disease. The methods of diagnosis include determining increased expression of enzymes that are upregulated during the progress of joint and ligament inflammation and degeneration. In addition, disclosed are methods of treating the disease including inhibiting the activity of responsible proteases.

US Patent:

20060025682, Feb 2, 2006

Filed:

Jul 29, 2005

Appl. No.:

11/192930

Inventors:

Ray Vanderby - Madison WI, US
Hirohito Kobayashi - Madison WI, US

International Classification:

A61B 8/00

US Classification:

600438000

Abstract:

The variation in acoustic properties in soft tissues, such as biological tissues, as a function of strain may be modeled to improve elastographic measurements and to obtain direct measurements of strain or material properties and pre-stress.

US Patent:

20120259224, Oct 11, 2012

Filed:

Apr 8, 2011

Appl. No.:

13/083038

Inventors:

William A. Sethares - Madison WI, US
Ray Vanderby - Madison WI, US

International Classification:

A61B 8/00

US Classification:

600443

Abstract:

An ultrasound machine provides for segmentation of tissue structure that may track isolated tissue structures over multiple frames of data taken over time. Analysis of the isolated tissue structure permits better discrimination of small differences between tissue structures such as may indicate tissue damage or disease.