Ray Vanderby - Madison WI, US Hirohito Kobayashi - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61B 8/00
US Classification:
600438, 600437, 600442, 600443, 600448, 310311
Abstract:
An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.
Ray Vanderby - Madison WI, US Kelley Dwyer Grorud - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 38/00 C07K 2/00
US Classification:
514 2, 530300
Abstract:
Disclosed are a method and a corresponding pharmaceutical composition for treating damaged ligaments. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of ligaments damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).
Use Of Neuropeptides For Traumatic Cartilage Injury
Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of cartilage and bone damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).
Method And Apparatus For Acoustoelastic Extraction Of Strain And Material Properties
Ray Vanderby - Madison WI, US Hirohito Kobayashi - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61B 8/00
US Classification:
600437, 600407, 600438, 600442, 600443
Abstract:
An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.
Method And Apparatus Using Lateral Access To Obtain Acoustoelastic Extraction Of Axial Material Properties
Ray Vanderby - Madison WI, US Hirohito Kobayashi - Madison WI, US
International Classification:
G06F 19/00 A61B 8/00
US Classification:
702 42, 600438
Abstract:
An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines.
Method To Diagnose And Treat Degenerative Joint Disease
Peter Muir - Madison WI, US Ray Vanderby - Madison WI, US Paolo Provenzano - Madison WI, US
International Classification:
C12Q001/68 C12Q001/37
US Classification:
435006000, 435023000
Abstract:
Disclosed are methods for detecting and treating joint disease. The methods of diagnosis include determining increased expression of enzymes that are upregulated during the progress of joint and ligament inflammation and degeneration. In addition, disclosed are methods of treating the disease including inhibiting the activity of responsible proteases.
Method And Apparatus Providing Improved Ultrasonic Strain Measurements Of Soft Tissue
Ray Vanderby - Madison WI, US Hirohito Kobayashi - Madison WI, US
International Classification:
A61B 8/00
US Classification:
600438000
Abstract:
The variation in acoustic properties in soft tissues, such as biological tissues, as a function of strain may be modeled to improve elastographic measurements and to obtain direct measurements of strain or material properties and pre-stress.
Ultrasound Machine For Improved Longitudinal Tissue Analysis
William A. Sethares - Madison WI, US Ray Vanderby - Madison WI, US
International Classification:
A61B 8/00
US Classification:
600443
Abstract:
An ultrasound machine provides for segmentation of tissue structure that may track isolated tissue structures over multiple frames of data taken over time. Analysis of the isolated tissue structure permits better discrimination of small differences between tissue structures such as may indicate tissue damage or disease.