Peter R Markham

US Patent:

20100228280, Sep 9, 2010

Filed:

Mar 9, 2009

Appl. No.:

12/400041

Inventors:

Adam Groothuis - Swampscott MA, US
Edward I. McNamara - Chelmsford MA, US
Peter Markham - Kingston NH, US
Elazer R. Edelman - Brookline MA, US

International Classification:

A61M 29/02
A61M 25/10
A61F 2/01

US Classification:

606200, 604 9601, 6041031

Abstract:

The invention provides a variety of catheters and methods for using such catheters. An exemplary catheter includes an elongate body having a proximal end a distal end. The elongate body defines a longitudinal axis of the catheter. The exemplary catheter further includes at least one inflatable member disposed on the elongate body proximate the distal end of the elongate body. The interior of the inflatable member is in fluid communication with an inflation lumen in the elongate body. The exemplary catheter also includes a first filter adapted and configured to capture emboli in a patient's bloodstream as the bloodstream passes through the first filter along a first direction. The exemplary catheter further includes a second filter adapted and configured to capture emboli in a patient's bloodstream as the bloodstream passes through the second filter along a second direction, wherein the second direction is generally opposite to the first direction.

US Patent:

20110112630, May 12, 2011

Filed:

Oct 6, 2010

Appl. No.:

12/899231

Inventors:

Adam Groothuis - Swampscott MA, US
Adrian Ebner - Asuncion, PY
Peter Markham - Kingston NH, US
Elazer R. Edelman - Brookline MA, US

International Classification:

A61F 2/24

US Classification:

623 21, 623 212

Abstract:

The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.

US Patent:

20130310924, Nov 21, 2013

Filed:

Apr 23, 2013

Appl. No.:

13/868226

Inventors:

Adam Groothuis - Swampscott MA, US
Adrian Ebner - Asuncion, PY
Peter Markham - Kingston NH, US
Elazer Edelman - Brookline MA, US

International Classification:

A61F 2/24

US Classification:

623 211

Abstract:

The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.

US Patent:

20210015615, Jan 21, 2021

Filed:

Jul 30, 2020

Appl. No.:

16/943606

Inventors:

Adam Groothuis - Swampscott MA, US
Adrian Ebner - Asuncion, PY
Peter Markham - Kingston NH, US
Elazer Edelman - Brookline MA, US

International Classification:

A61F 2/24

Abstract:

A partial valve prosthesis includes a framework configured for following a shape of a portion of the native valve annulus when implanted into the native valve annulus, the framework including securement features for anchoring the framework to an inner periphery of the native valve annulus and retaining at least one leaflet configured to replace a corresponding one of the plurality of native leaflets; and at least one leaflet secured to the framework. Additional embodiments and methods are disclosed.

US Patent:

20200352715, Nov 12, 2020

Filed:

Jul 30, 2020

Appl. No.:

16/943562

Inventors:

Adam Groothuis - Swampscott MA, US
Adrian Ebner - Asuncion, PY
Peter Markham - Kingston NH, US
Elazer Edelman - Brookline MA, US

International Classification:

A61F 2/24

Abstract:

The present embodiments relate to systems and methods for treating luminal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of luminal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.

US Patent:

20190060070, Feb 28, 2019

Filed:

Jul 16, 2018

Appl. No.:

16/036618

Inventors:

Adam Groothuis - Swampscott MA, US
Adrian Ebner - Asuncion, PY
Peter Markham - Kingston NH, US
Elazer Edelman - Brookline MA, US

International Classification:

A61F 2/24

Abstract:

A partial valve prosthesis includes a framework configured for following a shape of a portion of the native valve annulus when implanted into the native valve annulus, the framework including securement features for anchoring the framework to an inner periphery of the native valve annulus and retaining at least one leaflet configured to replace a corresponding one of the plurality of native leaflets; and at least one leaflet secured to the framework. Additional embodiments and methods are disclosed.

US Patent:

20170367705, Dec 28, 2017

Filed:

Jun 23, 2017

Appl. No.:

15/632233

Inventors:

- Newark DE, US
Elazer R. Edelman - Cambridge MA, US
Peter Heicksen - Flagstaff AZ, US
Theresa A. Holland - Flagstaff AZ, US
Peter M. Markham - Lexington MA, US
Peter D. Traylor - Flagstaff AZ, US
Abraham Tzafriri - Lexington MA, US
Brett G. Zani - Lexington MA, US

International Classification:

A61B 17/12
A61B 18/24
A61M 25/10
A61B 18/02

Abstract:

The present disclosure is directed toward drug coated balloons, and in particular to drug coated balloons having a microcrystalline structure and techniques for increasing vascular permeability for drug application and retention. Particular aspects may be directed to a medical device including a balloon having an outer surface, and a drug coating layer on the outer surface of the balloon. The drug coating layer includes microcrystals in a haystack orientation having random and a substantial absence of uniformity in placement and/or angle on the outer surface of the balloon.