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Michael W Hunkapiller

age ~73

from San Carlos, CA

Also known as:
  • Michael Hunkapiller
  • Mike Hunkapiller
  • Michael R
  • Mic Hunkapiller
1333 Pebble Dr, San Carlos, CA 94070

Michael Hunkapiller Phones & Addresses

  • 1333 Pebble Dr, San Carlos, CA 94070
  • San Gabriel, CA
  • Pasadena, CA
  • Yonkers, NY
  • Denver, CO
  • Redwood City, CA
  • Foster City, CA
  • Norwalk, CT

Wikipedia

Applied Biosystems

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In 1995, upon Andre Marion retirement, Mike Hunkapiller became President of PE .... Dr. Michael W. Hunkapiller remained as a Senior Vice President of PE ...

Name / Title
Company / Classification
Phones & Addresses
Michael Hunkapiller
President
PACIFIC BIOSCIENCES OF CALIFORNIA, INC. WHICH WILL DO BUSINESS IN CALIFORNIA AS PAC BIO, INC
1380 Willow Rd, Menlo Park, CA 94025
1505 Adams Dr, Menlo Park, CA 94025
Michael Hunkapiller
President, Chairman, Director
Pacific Biosciences
Biotechnology · Sales And Service Of Laboratory Equipment And Materials · Mfg Analytical Instruments
1380 Willow Rd, Menlo Park, CA 94025
1380 Willow Road  , Menlo Park, CA 94025
2711 Centerville Rd SUITE 400  , Wilmington, DE 19808
1505 Adams Dr, Menlo Park, CA 94025
650-543-5000
Michael Hunkapiller
Director M I S
Life Technologies Corporation
Diagnostic Substances, Nsk · Mfg Diagnostic Substances · Mfg Surgical/Medical Instruments
500 Lincoln Ctr Dr, San Mateo, CA 94404
101 Lincoln Ctr Dr, San Mateo, CA 94404
300 Lincoln Ctr Dr, San Mateo, CA 94404
700 Lincoln Ctr Dr, San Mateo, CA 94404
650-570-6667, 650-638-5800
Michael W. Hunkapiller
Director
FLUIDIGM CORPORATION
Commercial Physical Research · Mfg Laboratory Analytical Instruments · Mfg of Laboratory Analytical Instruments
7000 Shoreline Ct STE 100, South San Francisco, CA 94080
650-266-6000, 650-266-6106

Us Patents

  • Automated Dna Sequencing Technique

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  • US Patent:
    5747249, May 5, 1998
  • Filed:
    Dec 21, 1994
  • Appl. No.:
    8/361176
  • Inventors:
    Lloyd M. Smith - Madison WI
    Leroy E. Hood - Seattle WA
    Michael W. Hunkapiller - San Carlos CA
    Tim J. Hunkapiller - Seattle WA
    Charles R. Connell - Redwood City CA
  • Assignee:
    California Institute of Technology - Pasadena CA
  • International Classification:
    C12Q 168
    C12P 1934
    C07H 2104
  • US Classification:
    435 6
  • Abstract:
    A process for the electrophoretic analysis of DNA fragments produced in DNA sequencing operations wherein chromophores or fluorophores are used to tag the DNA fragments produced by the sequencing chemistry and permit the detection and characterization of the fragments as they are resolved by electrophoresis through a gel. Preferably four different fragment sets are tagged with the fluorophores fluorescein, Texas Red, tetramethyl rhodamine, and 7-nitro-benzofurazan. A system for the electrophoretic analysis of DNA fragments produced in DNA sequencing operations comprising: a source of chromophore or fluorescent tagged DNA fragments; a zone for contacting an electrophoresis gel; means for introducing said tagged DNA fragments to said zone; and photometric means for monitoring said tagged DNA fragments as they move through said gel.
  • Binary Probe And Clamp Composition And Methods For A Target Hybridization Detection

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  • US Patent:
    6432642, Aug 13, 2002
  • Filed:
    Jan 15, 1999
  • Appl. No.:
    09/232000
  • Inventors:
    Kenneth J. Livak - San Jose CA
    Michael Egholm - Wayland MA
    Michael W. Hunkapiller - San Carlos CA
  • Assignee:
    PE Corporation (NY) - Foster City CA
  • International Classification:
    C12Q 168
  • US Classification:
    435 6, 536 231, 536 243, 435 912, 935 76, 935 77, 935 78
  • Abstract:
    Binary probe and clamp compositions conduct methods for target hybridization detection. Where the probe is a substrate for exonuclease cleavage, the composition provides quantitation and detection of PCR products, by real-time and end-point measurements. Where the probe is an amplification primer, the composition provides an improved method for labelling and detection of PCR products. Probes and clamps may be labelled with fluorescent dyes, quenchers, hybridization-stabilizing moieties, chemiluminescent dyes, and affinity ligands. Clamps may be nucleic acid analogs, such as 2-aminoethylglycine PNA.
  • Binary Probe And Clamp Composition

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  • US Patent:
    7057025, Jun 6, 2006
  • Filed:
    Mar 28, 2002
  • Appl. No.:
    10/112677
  • Inventors:
    Kenneth J. Livak - San Jose CA, US
    Michael Egholm - Wayland MA, US
    Michael W. Hunkapiller - San Carlos CA, US
  • Assignee:
    Applera Corporation - Foster City CA
  • International Classification:
    C07H 21/02
    C07H 21/04
    C12Q 1/68
    C12P 19/34
  • US Classification:
    536 231, 536 243, 536 2431, 536 2432, 536 2433, 435 6, 435 911, 435 912, 435 915
  • Abstract:
    Binary probe and clamp compositions conduct methods for target hybridization detection. Where the probe is a substrate for exonuclease cleavage, the composition provides quantitation and detection of PCR products, by real-time and end-point measurements. Where the probe is an amplification primer, the composition provides an improved method for labelling and detection of PCR products. Probes and clamps may be labelled with fluorescent dyes, quenchers, hybridization-stabilizing moieties, chemiluminescent dyes, and affinity ligands. Clamps may be nucleic acid analogs, such as 2-aminoethylglycine PNA.
  • Methods And Compositions For Detecting Targets

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  • US Patent:
    7153658, Dec 26, 2006
  • Filed:
    Sep 19, 2003
  • Appl. No.:
    10/665671
  • Inventors:
    Mark R. Andersen - San Mateo CA, US
    Michael W. Hunkapiller - San Carlos CA, US
    Kenneth J. Livak - San Jose CA, US
    Eugene G. Spier - Palo Alto CA, US
    H. Michael Wenz - Redwood City CA, US
  • Assignee:
    Applera Corporation - Foster City CA
  • International Classification:
    C12Q 1/68
    C07H 21/02
    C07H 21/04
  • US Classification:
    435 6, 536 231, 536 243
  • Abstract:
    The present invention relates to methods and kits for detecting the presence or absence of (or quantitating) target nucleic acid sequences using ligation and amplification. The invention also relates to methods, reagents, and kits that employ addressable portions and labeled probes.
  • Methods And Kits For Methylation Detection

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  • US Patent:
    7364855, Apr 29, 2008
  • Filed:
    May 2, 2005
  • Appl. No.:
    11/119985
  • Inventors:
    Mark R. Andersen - Carlsbad CA, US
    Michael W. Hunkapiller - San Carlos CA, US
    Steven M. Menchen - Fremont CA, US
  • Assignee:
    Applera Corporation - Foster City CA
  • International Classification:
    C12Q 1/68
    C07H 21/02
    C07H 21/04
  • US Classification:
    435 6, 536 231, 536 243
  • Abstract:
    Ligation-based methods and kits are disclosed for determining the degree of methylation of one or more target nucleotides. In certain embodiments, the methylation status of one or more target nucleotides is determined by generating misligation products. In certain embodiments, at least one target nucleotide is amplified prior to the ligation reaction. In certain embodiments, at least one ligation product, at least one ligation product surrogate, at least one misligation product, at least one misligation product surrogate, or combinations thereof are amplified. In certain embodiments, one or more ligation probes comprise at least one nucleotide analog, at least one Modification, at least one mismatched nucleotide, or combinations thereof.
  • Binary Probe And Clamp Composition And Methods For Target Hybridization Detection

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  • US Patent:
    8067165, Nov 29, 2011
  • Filed:
    Aug 10, 2009
  • Appl. No.:
    12/538823
  • Inventors:
    Kenneth Livak - San Jose CA, US
    Michael Egholm - Madison CT, US
    Michael Hunkapiller - San Carlos CA, US
  • Assignee:
    Applied Biosystems, LLC - Carlsbad CA
  • International Classification:
    C12Q 1/68
    C07H 21/02
    C07H 21/04
  • US Classification:
    435 6, 536 243, 536 2431, 536 2432, 536 2433, 435 911, 435 912, 435 915
  • Abstract:
    Binary probe and clamp compositions conduct methods for target hybridization detection. Where the probe is a substrate for exonuclease cleavage, the composition provides quantitation and detection of PCR products, by real-time and end-point measurements. Where the probe is an amplification primer, the composition provides an improved method for labelling and detection of PCR products. Probes and clamps may be labelled with fluorescent dyes, quenchers, hybridization-stabilizing moieties, chemiluminescent dyes, and affinity ligands. Clamps may be nucleic acid analogs, such as 2-aminoethylglycine PNA.
  • Tagged Extendable Primers And Extension Products

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  • US Patent:
    RE43096, Jan 10, 2012
  • Filed:
    Mar 13, 2003
  • Appl. No.:
    10/389663
  • Inventors:
    Lloyd M. Smith - Madison WI, US
    Leroy E. Hood - Seattle WA, US
    Michael W. Hunkapiller - San Carlos CA, US
    Timothy Hunkapiller - Mercer Island WA, US
    Charles R. Connell - Redwood City CA, US
  • Assignee:
    California Institute of Technology - Pasadena CA
  • International Classification:
    C12Q 1/68
    G01N 27/447
  • US Classification:
    435 61, 536 243, 536 2532, 536 266, 435 912, 435 911, 435 9151
  • Abstract:
    This invention provides a duplex comprising an oligonucleotide primer and a template, wherein the primer is coupled chemically to a chromophore or fluorophore so as to allow chain extension by a polymerase. In one embodiment, the primer is extended by a polymerase to generate the complement of the template. In a further embodiment, the extended primer is separated from the template for use in a number of methods, including sequencing reactions. Methods of generating these compositions of matter are further provided.
  • Automated Dna Sequencing Technique

    view source
  • US Patent:
    20020123046, Sep 5, 2002
  • Filed:
    Feb 2, 2001
  • Appl. No.:
    09/776291
  • Inventors:
    Lloyd Smith - Madison WI, US
    Leroy Hood - Seattle WA, US
    Michael Hunkapiller - San Carlos CA, US
    Tim Hunkapiller - Seattle WA, US
    Charles Connell - Redwood City CA, US
  • International Classification:
    C12Q001/68
    C07H021/04
  • US Classification:
    435/006000, 536/025320
  • Abstract:
    A process for the electrophoretic analysis of DNA fragments produced in DNA sequencing operations wherein chromophores or fluorophores are used to tag the DNA fragments produced by the sequencing chemistry and permit the detection and characterization of the fragments as they are resolved by electrophoresis through a gel. Preferably four different fragment sets are tagged with the fluorophores fluorescein, Texas Red, tetramethyl rhodamine, and 7-nitro-benzofurazan. A system for the electrophoretic analysis of DNA fragments produced in DNA sequencing operations comprising: a source of chromophore or fluorescent tagged DNA fragments; a zone for contacting an electrophoresis gel; means for introducing said tagged DNA fragments to said zone; and photometric means for monitoring said tagged DNA fragments as they move through said gel.

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