Mercy A Otteng from North Haven, CT, age 47

Substituted Isoquinoline-1,3(2H,4H)-Diones, 1-Thioxo-1,4-Dihydro-2H-Isoquinoline-3-Ones And 1,4-Dihydro-3 (2H)-Isoquinolones And Methods Of Use Thereof
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US Patent:

20080085890, Apr 10, 2008
Filed:

Mar 26, 2007
Appl. No.:

11/728897
Inventors:

Gary Birnberg - Tuxedo Park NY, US
Middleton Floyd - Suffern NY, US
Joshua Kaplan - Nyack NY, US
Kristina Kutterer - Westwood NJ, US
Xiaoxiang Liu - River Vale NJ, US
Ramaswamy Nilakantan - Closter NJ, US
Mercy Otteng - Pearl River NY, US
Zhilian Tang - Edgewater NJ, US
Arie Zask - New York NY, US
Tritin Tran - King of Prussia PA, US
Scott Mayer - Bridgewater NJ, US
Annette Banker - Plainsboro NJ, US
Marvin Reich - Sante Fe NM, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/55
A61K 31/47
A61K 31/496
A61K 31/497
A61K 31/501
A61P 1/00
A61P 17/06
A61P 3/10
A61P 31/12
C07D 295/00
C07D 241/02
C07D 239/02
C07D 237/26
C07D 237/02
C07D 223/02
C07D 217/00
A61P 9/00
A61P 35/00
A61P 31/10
A61P 19/02
A61P 11/00
A61K 31/502
A61K 31/506
A61K 31/5377
A61K 31/541
US Classification:

514217070, 514228200, 514235200, 514248000, 514252020, 514252110, 514252180, 514253050, 514309000, 540597000, 544128000, 544235000, 544238000, 544295000, 544357000, 544363000, 544062000, 546142000
Abstract:

This invention provides compounds of Formula (I), having the structure

Sulfamoyl-Containing Derivatives And Uses Thereof
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US Patent:

20080096903, Apr 24, 2008
Filed:

Oct 19, 2007
Appl. No.:

11/875320
Inventors:

Jianxin Chen - Littleton MA, US
Gerhard Sperl - Salem NH, US
Vincent Gullo - Basking Ridge NJ, US
Lalitha Sista - Moula Ali, IN
Dallas Hughes - Milford MA, US
Yucai Peng - Shrewsbury MA, US
William Pierceall - Sudbury MA, US
Andrew Weiskopf - Needham MA, US
Jeremy Levin - New City NY, US
Russell Dushin - Garrison NY, US
Mercy Otteng - Pearl River NY, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/52
C07D 207/00
C07D 235/04
C07D 239/00
C07D 249/16
C07D 295/22
C07D 471/02
C07D 473/00
C07D 487/00
C07D 498/02
US Classification:

514263100, 544254000, 544262000, 544277000, 544280000, 546113000, 546117000, 546118000, 548257000, 548304700, 548400000, 548541000, 548542000, 548544000
Abstract:

Sulfamoyl-containing compounds are disclosed, having utility as inhibitors of disease-related targets, such as Heat Shock Protein 90 (HSP90), and which are useful for treating disorders, e.g., proliferative disorders, including HSP90-mediated disorders. Methods for preparing and using the disclosed compounds are also described.

3-Substituted-1H-Indole Compounds, Their Use As Mtor Kinase And Pi3 Kinase Inhibitors, And Their Syntheses
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US Patent:

20090311217, Dec 17, 2009
Filed:

May 28, 2009
Appl. No.:

12/473605
Inventors:

Matthew Gregory Bursavich - Salt Lake City UT, US
Nan Zhang - Bayside NY, US
James Thomas Anderson - Hillsdale NJ, US
Thai Hiep Nguyen - Fair Lawn NJ, US
Sabrina Lombardi - New Haven CT, US
David Malwitz - Hopewell Junction NY, US
Natasja Brooijmans - New York NY, US
Derek Cecil Cole - New City NY, US
Adam Matthew Gilbert - Congers NY, US
Pawel Wojciech Nowak - Woodcliff Lake NJ, US
Kaapjoo Park - Congers NY, US
Sasmita Das - West Nyack NY, US
Aranapakam Mudumbai Venkatesan - Rego Park NY, US
Mercy Adufa Otteng - Pearl River NY, US
Gary Harold Birnberg - Tuxedo Park NY, US
Gloria Jean MacEwan - Monroe NY, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/404
C07D 405/02
C07D 403/14
C07D 413/02
A61K 31/496
A61K 31/5377
A61K 38/21
A61K 39/395
A61P 35/00
US Classification:

424 856, 548454, 544373, 544121, 514414, 51425409, 5142352, 4241331
Abstract:

The invention relates to 3-substituted-1H-indole compounds of the Formula I:or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.

4-Aryloxyquinolin-2(1H)-Ones As Mtor Kinase And Pi3 Kinase Inhibitors, For Use As Anti-Cancer Agents
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US Patent:

20100068204, Mar 18, 2010
Filed:

Sep 14, 2009
Appl. No.:

12/558661
Inventors:

Gary Harold Birnberg - Tuxedo Park NY, US
Gloria Jean MacEwan - Monroe NY, US
Mercy Adufa Otteng - Pearl River NY, US
Pawel Wojciech Nowak - Woodcliff Lake NJ, US
Tarek Suhayl Mansour - New City NY, US
Arie Zask - New York NY, US
Ker Yu - Pine Brook NJ, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 39/395
C07D 215/00
A61K 31/47
US Classification:

4241331, 546155, 514312
Abstract:

Compounds of the formula Iand pharmaceutically acceptable salts thereof, wherein A, B, R, R, R, R, R, R, and Rare defined as set forth herein are disclosed. Also disclosed are pharmaceutical compositions comprising the compounds of the invention and a pharmaceutically acceptable carrier, methods of making the compounds of the invention and methods of using the compounds for inhibiting mTOR and PI3 kinases and for treating cancers.

Mercy A Otteng