Masaki Tomimoto from Boston, MA, age 55

Compound Libraries And Methods For Drug Discovery
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US Patent:

20040265909, Dec 30, 2004
Filed:

Apr 9, 2004
Appl. No.:

10/821662
Inventors:

Jeff Blaney - Piedmont CA, US
Ian McDonald - San Diego CA, US
Masaki Tomimoto - San Diego CA, US
International Classification:

G01N033/53
G01N033/543
US Classification:

435/007100, 436/518000
Abstract:

The present invention provides compound libraries that can be rapidly and efficiently synthesized for use in lead discovery and design, and can be easily expanded for further drug discovery. The present invention also provides methods of using such compound libraries to design and identify novel drug leads.

Crystals And Structures Of Spleen Tyrosine Kinase Sykkd
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US Patent:

20040253178, Dec 16, 2004
Filed:

Dec 17, 2003
Appl. No.:

10/738575
Inventors:

Shane Atwell - Encinitas CA, US
Jorg Hendle - San Diego CA, US
Sean Buchanan - Encinitas CA, US
Ingeborg Feil - San Diego CA, US
Marijane Russell - Solana Beach CA, US
John Badger - San Diego CA, US
Masaki Tomimoto - San Diego CA, US
Michael Sauder - Carlsbad CA, US
International Classification:

G06F019/00
G01N033/48
G01N033/50
US Classification:

424/001690, 530/350000, 702/019000
Abstract:

The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of SYKKD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of SYKKD, and compounds and compositions that affect SYK activity.

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Masaki Tomimoto