Laxma G Reddy

US Patent:

20110229457, Sep 22, 2011

Filed:

Mar 11, 2011

Appl. No.:

13/046547

Inventors:

Timothy M. Kloke - Victoria MN, US
Joram Slager - St. Louis Park MN, US
Laxma Gundlapally Reddy - Shoreview MN, US
David E. Babcock - St. Louis Park MN, US

Assignee:

SurModics, Inc. - Eden Prairie MN

International Classification:

A61K 39/395
A61K 47/36
A61K 38/02
A61K 38/43
A61K 31/713
A61P 25/28
A61P 25/16
A61P 25/00
A61P 27/02
A61P 27/06
A61P 31/20
A61P 31/14
A61P 19/02
A61K 31/7088
A61K 31/7052

US Classification:

4241301, 514777, 514 11, 424 941, 514 44 A, 514778, 514 44 R, 514 43

Abstract:

The invention provides a formulation that includes a biocompatible solvent system, a biodegradable polymer that is substantially soluble in the biocompatible solvent system, and an active pharmaceutical ingredient that is substantially insoluble in the biocompatible solvent system. The formulation can form a drug-eluting implant, when injected into mammalian tissue. The solvent system and the biodegradable polymer can be selected so that the implant provides extended, delayed, controlled and/or modified release of the active pharmaceutical ingredient, for example, over the course of days, weeks or months.

US Patent:

20170354611, Dec 14, 2017

Filed:

Aug 25, 2017

Appl. No.:

15/687366

Inventors:

- New York NY, US
Robert Jennings - San Diego CA, US
Nikita Malavia - San Diego CA, US
Laxma Reddy - San Diego CA, US
Norman Betty - San Diego CA, US

International Classification:

A61K 9/50
A61K 31/433
A61K 31/542

Abstract:

Microparticles are prepared by a method that includes: (a) forming a layer comprising a first polymer on a solid surface by depositing a first composition one or more times on the solid surface, wherein the first composition comprises the first polymer and a first solvent, and evaporating the first solvent in the first composition; (b) forming one or more layers comprising a second polymer and a therapeutic agent by depositing a second composition on all or part of the layer formed in step (a), wherein the second composition comprises the second polymer, the therapeutic agent, and a second solvent; and evaporating the second solvent in the second composition; and (c) forming an additional layer comprising a third polymer by depositing a third composition one or more times on a previously formed layer, wherein the third composition comprises the third polymer and a third solvent; and evaporating the third solvent in the third composition.

US Patent:

20140093552, Apr 3, 2014

Filed:

Sep 20, 2013

Appl. No.:

14/033331

Inventors:

- Great Neck NY, US
Robert Jennings - San Diego CA, US
Chris Rhodes - San Diego CA, US
Laxma Reddy - San Diego CA, US
Norman Betty - San Diego CA, US

Assignee:

SKS Ocular, LLC - Great Neck NY

International Classification:

A61K 9/50

US Classification:

424422, 424497, 514 11, 514 54, 514 44 R, 4241301, 427 21

Abstract:

Microparticles are prepared by a method that includes: (a) forming a layer comprising a first polymer on a solid surface by depositing a first composition one or more times on the solid surface, wherein the first composition comprises the first polymer and a first solvent, and evaporating the first solvent in the first composition; (b) forming one or more layers comprising a second polymer and a therapeutic agent by depositing a second composition on all or part of the layer formed in step (a), wherein the second composition comprises the second polymer, the therapeutic agent, and a second solvent; and evaporating the second solvent in the second composition; and (c) forming an additional layer comprising a third polymer by depositing a third composition one or more times on a previously formed layer, wherein the third composition comprises the third polymer and a third solvent; and evaporating the third solvent in the third composition.