Mark J. Roth - Chevy Chase MD, US Konrad Huppi - Herndon VA, US
Assignee:
The United States of America as represented by the Secretary, Department of Health & Human Services - Washington DC
International Classification:
C12Q 1/68 G01N 33/574
US Classification:
435 61, 435 721, 435 723
Abstract:
The invention relates to method of diagnosing and treating cancer, in particular β-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics.
Method Of Diagnosing And Treating Cancer Using B-Catenin Splice Variants
The invention relates to method and compositions for treating and diagnosing cancer, in particular β-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics.
Method Of Detecting A Predisposition To Cancer By The Use Of Restriction Fragment Length Polymorphism Of The Gene For Human Poly (Adp-Ribose) Polymerase
Mark E. Smulson - Washington DC Kishor Bhatia - Arbutus MD Konrad Huppi - Reston VA
Assignee:
Georgetown University - Washington DC
International Classification:
C12Q 168 C07H 2104
US Classification:
435 6
Abstract:
The invention relates to a method for detecting the presence of a DNA polymorphism associated with predisposition for certain cancers in a human. This method involves analyzing the human chromosome 13 using a hybridization probe which will hybridize to the gene for human poly (ADP-ribose) polymerase wherein the probe is capable of identifying the DNA polymorphism.
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Washington Figure Skating Club Amusement/Recreation Services