Kerry W Kissinger

US Patent:

43904998, Jun 28, 1983

Filed:

Aug 13, 1981

Appl. No.:

6/292384

Inventors:

Huntington W. Curtis - Chelsea NY
Robert M. Kellogg - Washington Crossing PA
Kerry W. Kissinger - Pennington NJ
Robert P. Mappes - Cranbury NJ
Emery J. Stephans - Plainsboro NJ

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G01N 2107
G01N 3500

US Classification:

422 72

Abstract:

Apparatus for carrying out in situ chemical analysis of biological fluids is disclosed. A test package adapted for use with spinning rotor includes a sample-compartment, an integral cuvette and compartments for prepackaged reagents. The latter are adapted to be introduced via breakable seals into the sample compartment which contains the sample to be analyzed. The sample and reagents are then introduced via another breakable seal into a cuvette. Under pneumatic and rotational forces, mixing and measuring are carried out in situ. The rotor includes a programmable pressure applying arrangement whereby the dispensing of reagents and the movement of the latter and sample into a cuvette are controlled. Optical measurements are then carried out in situ.