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Kenneth L Dretchen

from Gaithersburg, MD

Also known as:
  • K Dretchen
  • Kenneth Gretchen
  • Kenneth L living trus Dretchen
12628 Triple Crown Rd, Gaithersburg, MD 20878301-977-0071

Kenneth Dretchen Phones & Addresses

  • 12628 Triple Crown Rd, North Potomac, MD 20878 • 301-977-0071
  • 834 Highland Ridge Ave, Gaithersburg, MD 20878
  • Silver Spring, MD
  • Mount Airy, MD
  • 140 Chevy Chase St APT 306, Gaithersburg, MD 20878 • 301-977-0071

Work

  • Position:
    Educator

Education

  • Degree:
    Graduate or professional degree

Us Patents

  • Sequence-Specific Detection Of Nucleotide Sequences

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  • US Patent:
    20120065088, Mar 15, 2012
  • Filed:
    Feb 23, 2010
  • Appl. No.:
    13/202887
  • Inventors:
    Mark Danielsen - Germantown MD,
    Joel Credle - Washington DC,
    Eugene A. Davidson - Boynton Beach FL,
    Kenneth L. Dretchen - North Potomac MD,
  • Assignee:
    Georgetown University - Washington DC
  • International Classification:
    C40B 30/04
    C12Q 1/70
    C12Q 1/68
    C07H 1/00
    C07H 21/04
    C40B 40/06
  • US Classification:
    506 9, 536 243, 506 16, 435 611, 536 2432, 536 253, 435 5
  • Abstract:
    A method for detecting the presence of a target nucleotide sequence in a sample of DNA is described herein in which a test sample comprising single stranded DNA is exposed to a DNA probe and a nicking endonuclease under conditions that would permit sequence-specific hybridization of the probe to a complementary target sequence. The probe comprises a sequence complementary to the target sequence to be detected and this sequence also includes a recognition sequence for the nicking endonuclease. If the sample contains the target sequence, the probe hybridizes to the target and is cleaved by the nicking endonuclease, which leaves the target intact. Observing the presence of probe cleaved by the nicking endonuclease indicates the presence of the target nucleotide sequence in the sample of DNA.
  • Sequence-Specific Detection Of Nucleotide Sequences

    view source
  • US Patent:
    20110123980, May 26, 2011
  • Filed:
    Feb 15, 2006
  • Appl. No.:
    11/884366
  • Inventors:
    Mark Danielsen - Germantown MD,
    Eugene A. Davidson - Washington DC,
    Kenneth L. Dretchen - North Potomac MD,
    Traci L. Pals - Alexandria VA,
  • Assignee:
    GEORGETOWN UNIVERSITY - Washington DC
  • International Classification:
    C12Q 1/68
  • US Classification:
    435 6
  • Abstract:
    A method for detecting the presence of a target nucleotide sequence in a sample of DNA is described herein in which a test sample comprising single stranded DNA is exposed to a DNA probe and a nicking endonuclease under conditions that would permit sequence-specific hybridization of the probe to a complementary target sequence. The probe comprises a sequence complementary to the target sequence to be detected and this sequence also includes a recognition sequence for the nicking endonuclease. If the sample contains the target sequence, the probe hybridizes to the target and is cleaved by the nicking endonuclease, which leaves the target intact. Observing the presence of probe cleaved by the nicking endonuclease indicates the presence of the target nucleotide sequence in the sample of DNA.

Resumes

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Kenneth Dretchen

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