Bhavin Shah - West Lafayette IN, US Katie L. Harrigan - Cordova TN, US
International Classification:
A61K 38/39
US Classification:
514 172
Abstract:
Described are purified extracellular matrix materials isolated from the abdominal wall of animals and including the subserous fascia layer of the abdominal wall. Such medical materials can find use in treating damaged tissue and in certain aspects in providing tissue support for the repair of hernias. Related methods of manufacture and use are also described.
Isolated Extracellular Matrix Material Including Subserous Fascia
Described are purified extracellular matrix materials isolated from the abdominal wall of animals and including the subserous fascia layer of the abdominal wall. Such medical materials can find use in treating damaged tissue and in certain aspects in providing tissue support for the repair of hernias. Related methods of manufacture and use are also described.
Kits For Preparing A Reactive Graft Material And Injecting The Graft Material Into A Patient
Disclosed are kits for preparing a reactive graft material and injecting the graft material into a patient. Kits may include a first syringe containing a first powdered component and a second syringe containing a second powdered component that is reactive with the first powdered component when the first and second powdered components are dispersed in a diluent solution. The kits may further include a vial sealed by a septum and containing the diluent solution. A syringe connector may be included that has a connector at each end configured to make a fluidic connection to, respectively, the first syringe and the second syringe, and also comprises a passageway adapted to allow fluid to pass between the syringes when the syringes are both fluidically connected to the syringe connector. A vial adapter comprising a connector adapted for fluidically connecting to at least one of the first syringe and the second syringe, a passageway adapted to allow fluid to pass from the vial into a syringe fluidically connected to the connector of the vial adapter, and a spike in fluidic communication with the passageway of the vial adapter may be included. The spike is adapted for piercing the septum of the vial. Certain kits also contain one or more needles for delivery of the graft material to a site within a body of a patient.
The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous β-tricalcium phosphate powder; and iv) a porous β-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
- Memphis TN, US Jamie Macdougall - Oakland TN, US Katie Harrigan - Cordova TN, US
Assignee:
Wright Medical Technology, Inc. - Memphis TN
International Classification:
A61L 24/02 C04B 28/14 A61L 24/00 C04B 28/34
Abstract:
The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous β-tricalcium phosphate powder; and iv) a porous β-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous β-tricalcium phosphate powder; and iv) a porous β-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
Bsi
Global Head - General Devices
Bsi
Technical Team Manager
Bsi
Product Expert and Scheme Manager
Agnovos Healthcare Sep 2013 - Aug 2014
Senior Project Engineer
Wright Medical Sep 2010 - Sep 2013
Senior Product Development Engineer
Education:
Rose - Hulman Institute of Technology 2006 - 2007
Master of Science, Masters, Biomedical Engineering
Rose - Hulman Institute of Technology 2002 - 2006
Bachelors, Medical Engineering
Skills:
Medical Devices Biomaterials Design Control Biomedical Engineering Iso 13485 Fda R&D V&V Product Development Quality System Commercialization Capa Iso 14971 Tissue Engineering Orthopedic Design of Experiments Orthopedics Mechanical Testing Life Sciences Minitab Design For Manufacturing Surgical Instruments Biomechanics Technology Transfer Bioengineering Spine 21 Cfr 510 K Quality Systems Engineering Bone Biocompatibility Matlab Doe Iso Materials
Certifications:
License 912094 American Association of Tissue Banks, License 912094 Certified Tissue Bank Specialist
Sep 2013 to 2000 Sr. Project EngineerWright Medical Technology Arlington, TN Sep 2010 to Sep 2013 Project EngineerBioscience Vaccines Incorporated West Lafayette, IN Nov 2009 to Sep 2010 Founder and Vice President of Product DevelopmentCook Biotech Incorporated West Lafayette, IN Aug 2007 to Nov 2009 Research EngineerRose-Hulman Institute of Technology Terre Haute, IN Jun 2006 to Aug 2007 Research AssistantNSF Chicago, IL Jun 2005 to Aug 2005 Research FellowRose-Hulman Institute of Technology Terre Haute, IN Jun 2003 to Mar 2005 Undergraduate Research Assistant
Education:
Rose-Hulman Institute of Technology Terre Haute, IN Aug 2007 Master of Science in Biomedical EngineeringRose-Hulman Institute of Technology Terre Haute, IN May 2006 Ph.D. in Biomedical Engineering