Juliana K Kretsinger

US Patent:

20070128175, Jun 7, 2007

Filed:

Nov 14, 2006

Appl. No.:

11/598763

Inventors:

Bulent Ozbas - North Bergen NJ, US
Juliana Kretsinger - Martinsville IN, US
Lisa Butterick - Wilmington DE, US
Karthikan Rajagopal - Wilmington DE, US
Darrin Pochan - Landenberg PA, US
Joel Schneider - Newark DE, US

International Classification:

A61K 35/12
A61K 38/10
G01N 33/53
A61K 9/14

US Classification:

424093700, 514013000, 424488000, 435007100

Abstract:

The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions.

US Patent:

20110052692, Mar 3, 2011

Filed:

Jul 30, 2010

Appl. No.:

12/847476

Inventors:

Bulent Ozbas - North Bergen NJ, US
Juliana Kretsinger - Martinsville IN, US
Lisa A. Butterick - Wilmington DE, US
Karthikan Rajagopal - Wilmington DE, US
Darrin J. Pochan - Landenberg PA, US
Joel P. Schneider - Newark DE, US

Assignee:

University of Delaware - Newark DE

International Classification:

A61K 9/10
C07K 7/08
A61K 38/02
A61K 35/12
C12N 5/071
G01N 33/00
C07K 1/14
A61P 17/02

US Classification:

424484, 530326, 514 11, 424 937, 435325, 435366, 435326, 436 86, 530412, 5303871

Abstract:

The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions.