Search

Jerry W Skiles

age ~76

from Berlin, MA

Also known as:
  • Jerry Dr Skiles
  • Drjerry W Skiles
  • Jerry W Gonnella
  • Jerry W Skilles
Phone and address:
30 Autumn Rdg, Berlin, MA 01503

Jerry Skiles Phones & Addresses

  • 30 Autumn Rdg, Berlin, MA 01503
  • 1 Holly Ridge Ct, Bernardsville, NJ 07924
  • Chatham, NJ
  • Marlborough, MA
  • Tuckahoe, NY
  • Brookfield, CT
  • New Providence, NJ

Us Patents

  • Certain Azacycloalkyl Substituted Acetic Acid Derivatives

    view source
  • US Patent:
    20040235896, Nov 25, 2004
  • Filed:
    May 13, 2004
  • Appl. No.:
    10/471245
  • Inventors:
    Roger Fujimoto - Morristown NJ, US
    Leslie McQuire - Warren NJ, US
    Lauren Monovich - Summit NJ, US
    Philippe Nantermet - Lansdale PA, US
    David Parker - Livingston NJ, US
    Leslie Robinson - Del Mar CA, US
    Jerry Skiles - New Providence NJ, US
    Ruben Tommasi - Whitehouse Station NJ, US
  • International Classification:
    A61K031/445
    C07D211/32
    A61K031/55
    A61K031/40
  • US Classification:
    514/317000, 546/232000, 546/233000, 514/408000, 514/217120
  • Abstract:
    Compounds of the formula (I) wherein R represents OH or NHOH; Rrepresents hydrogen, optionally substituted lower alkyl, aryl-lower alkyl, cycloalkyl-lower alkyl, or acyl derived from a carboxylic acid, from a carbonic acid, from a carbamic acid of from a sulfonic acid; Rrepresents biarylsulfonyl or aryloxyarylsufonyl; Rrepresents hydrogen, optionally substituted lower alkyl, aryl-lower alkyl, cycloalkyl-lower alkyl or acyl derived from a carboxylic acid, from a carbonic acid or form a carbamic acid; Rand Rrepresent independently hydrogen, lower alkyl, lower alkoxycarbonyl, aryl-lower alkyl or cycloalkyl-lower alkyl; m is zero, 1, 2 or 3; pharmaceutically acceptable prodrug derivatives thereof; pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising said compounds; and their use for inhibiting matrix degrading metalloproteinases and preventing or treating matrix metalloproteinase dependent conditions in mammals.
  • Antihypertensive Derivatives

    view source
  • US Patent:
    47496983, Jun 7, 1988
  • Filed:
    Jul 8, 1985
  • Appl. No.:
    6/752695
  • Inventors:
    Edward S. Neiss - New Canaan CT
    John T. Suh - Greenwich CT
    John R. Regan - Mamaroneck NY
    Jerry W. Skiles - Tuckahoe NY
    Jeffrey N. Barton - New York NY
    James J. Mencel - Norwalk CT
    Paul Menard - Tuckahoe NY
  • Assignee:
    Rorer Pharmaceutical Corporation - Fort Washington PA
  • International Classification:
    C07D20712
    C07D20714
    C07D20724
    C07D41712
    C07D40312
    A61K 3154
    A61K 31505
    A61K 3140
    A61K 31495
  • US Classification:
    5142232
  • Abstract:
    Compounds having the general structure ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are defined herein, which exhibit antihypertensive activity.
  • Antihypertensive Amides

    view source
  • US Patent:
    45489289, Oct 22, 1985
  • Filed:
    Nov 19, 1984
  • Appl. No.:
    6/672651
  • Inventors:
    John T. Suh - Greenwich CT
    Jerry W. Skiles - Tuckahoe NY
    Bruce E. Williams - Cottage Crove MN
    Alfred Schwab - Williston Park NY
  • Assignee:
    USV Pharmaceutical Co. - Tarrytown NY
  • International Classification:
    A61K 2700
    C07D26532
    C07D26530
  • US Classification:
    514232
  • Abstract:
    Compounds of the structure: ##STR1## wherein R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5, and R. sub. 6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, n is an integer from 0 to 4 inclusive, M is heterocyclic or heterocyclic alkyl, Y is hydroxy, alkoxy, amino, or substituted amino, amino-alkanoyl, aryloxy, aminoalkoxy, or hydroxyalkoxy, and R. sub. 7 is hydrogen, alkanoyl, carboxylalkanoyl, hydroxyalkanoyl, amino-alkanoyl, cyano, amidino, carbalkoxy, ##STR2## wherein Z is hydrogen, alkyl, hydroxyalkyl, aminoalkyl or the radical ##STR3## wherein R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5, R. sub. 6, n, M and Y are as described above; and where Y is hydroxy their nontoxic, pharmaceutically acceptable alkali metal, alkaline earth metal, and amine salts.
  • Angiotensin-Converting Enzyme Inhibitors

    view source
  • US Patent:
    47030372, Oct 27, 1987
  • Filed:
    Feb 18, 1986
  • Appl. No.:
    6/830422
  • Inventors:
    Fu-chih Huang - Boonton NJ
    John T. Suh - Greenwich CT
    Jerry W. Skiles - Tuckahoe NY
  • Assignee:
    Rorer Pharmaceutical Corporation - Fort Washington PA
  • International Classification:
    A61K 3702
    C07D21700
    C07C 6106
    C07C 6104
    C07C 6108
  • US Classification:
    514 19
  • Abstract:
    Compounds of the formula ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.
  • Cyclic Amides

    view source
  • US Patent:
    52004163, Apr 6, 1993
  • Filed:
    May 12, 1980
  • Appl. No.:
    6/148083
  • Inventors:
    John T. Suh - Greenwich CT
    Jerry W. Skiles - Tuckahoe NY
    Bruce E. Williams - Cottage Grove MN
  • Assignee:
    USV Pharmaceutical Corporation - Tuckahoe NY
  • International Classification:
    A61K 3147
    C07D21716
  • US Classification:
    514307
  • Abstract:
    Compounds of the formula ##STR1## wherein: R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 6, and R. sub. 7 are independently hydrogen or lower alkyl. R. sub. 5 is hydrogen, lower alkyl, rad alkanoyl having 1 to 6 carbon atoms. Y is OH or OM wherein M is a pharmaceutically acceptable cation, and n is an integer from 0 to 1, and X. sub. 1 and X. sub. 2 are independently (CR. sub. 8 R. sub. 9). sub. m wherein R. sub. 8 and R. sub. 9 are independently hydrogen or lower alkyl and m is an integer from 1 to 5 are potent angiotensin converting enzyme inhibitors and possess antihypertensive activity.
  • Antihypertensive Amides

    view source
  • US Patent:
    43047718, Dec 8, 1981
  • Filed:
    Oct 24, 1980
  • Appl. No.:
    6/200180
  • Inventors:
    John T. Suh - Greenwich CT
    Jerry W. Skiles - Tuckahoe NY
    Bruce E. Williams - Cottage Crove MN
    Alfred Schwab - Williston Park NY
  • Assignee:
    USV Pharmaceutical Corporation - Tuckahoe NY
  • International Classification:
    C07D29502
    A61K 3154
    A61K 3138
  • US Classification:
    424246
  • Abstract:
    Compounds of the structure: ##STR1## wherein R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5, and R. sub. 6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, n is an integer from 0 to 4 inclusive, M is heterocyclic or heterocyclic alkyl, Y is hydroxy, alkoxy, amino, or substituted amino, amino-alkanoyl, aryloxy, aminoalkoxy, or hydroxyalkoxy, and R. sub. 7 is hydrogen, alkanoyl, carboxylalkanoyl, hydroxyalkanoyl, amino-alkanoyl, cyano, amidino, carbalkoxy, ZS, or ##STR2## wherein Z is hydrogen, alkyl, kydroxyalkyl, aminoalkyl or the radical ##STR3## wherein R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5, R. sub. 6, n, M and Y are as described above; and where Y is hydroxy their nontoxic, pharmaceutically acceptable alkali metal, alkaline earth metal, and amine salts.
  • Antihypertensive 1,4-Thiazepine-Ones, 1,4-Thiazonine-Ones, And Method Of Use Thereof

    view source
  • US Patent:
    42872030, Sep 1, 1981
  • Filed:
    Apr 23, 1980
  • Appl. No.:
    6/142945
  • Inventors:
    John T. Suh - Greenwich CT
    Bruce E. Williams - Cottage Grove MN
    Jerry W. Skiles - Tuckahoe NY
    Bernard Loev - Scarsdale NY
  • Assignee:
    USV Pharmaceutical Corporation - Tuckahoe NY
  • International Classification:
    A61K 3155
    C07D28104
    C07D28118
  • US Classification:
    424275
  • Abstract:
    Antihypertensive compounds of the structure ##STR1## wherein: n is an integer from 0 to 2 inclusive, R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5, R. sub. 6, and R. sub. 7 are independently hydrogen, alkyl having from 1 to 6 carbon atoms, alkenyl having from 2 to 6 carbon atoms, alkynyl having from 2 to 6 carbon atoms, cycloalkyl having from 3 to 16 carbon atoms, phenyl, benzyl, tolyl, naphthyl, phenethyl, indanyl, tetrahydronaphthyl, decanydronaphthyl, pyridyl, quinolyl, pyrrolidyl, pyrrolyl, morpholinyl, thiomorpholinyl, furyl, furfuryl, tetrahydrofurfuryl, benzimidazole, thienyl, imidolyl, or tetrahydroindolyl, and where the R. sub. 1 to R. sub. 7 groups are alkyl, said groups carrying a substituent selected from hydroxy, alkoxy, amino, carboxy, or carbalkoxy, the alkyl group in alkoxy and carbalkoxy having from 1 to 6 carbon atoms, or R. sub. 2 taken together with R. sub. 3 and the carbons to which they are attached is tetrahydronaphthyl or phenyl, and when phenyl R. sub. 1 and R. sub.
  • Angiotensin-Converting Enzyme Inhibitors

    view source
  • US Patent:
    45857580, Apr 29, 1986
  • Filed:
    Jan 10, 1985
  • Appl. No.:
    6/690386
  • Inventors:
    Fu-chih Huang - Boonton NJ
    John T. Suh - Greenwich CT
    Jerry W. Skiles - Tuckahoe NY
  • Assignee:
    USV Pharmaceutical Corp. - Tarrytown NY
  • International Classification:
    A61K 3147
    A61K 3764
    C07K 506
    C07D21706
  • US Classification:
    514 19
  • Abstract:
    Compounds of the formula ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.

Resumes

Jerry Skiles Photo 1

Executive Vice President Chemistry

view source
Location:
30 Autumn Rdg, Berlin, MA 01503
Industry:
Biotechnology
Work:
Valis Pharmaceuticals
Executive Vice President Chemistry

Biopredict
Director of Medicinal Chemistry
Education:
Kent State University
Bachelors, Bachelor of Science, Chemistry
University of Pennsylvania
Doctorates, Doctor of Philosophy, Organic Chemistry
Skills:
High Throughput Screening
Drug Design
Combinatorial Chemistry
Small Molecules
Protein Kinases
Chemistry
Hplc
Organic Synthesis
Assay Development
Fragment Based Lead
Biotechnology
Ind
Online Communications
Inflammation
Life Sciences
Adme
Drug Discovery
Analytical Chemistry
Lifesciences
Organic Chemistry
High Throughput
Oncology
Lead Change
Drug Development
Scifinder
Gpcrs
Pharmacology
Medicinal Chemistry
Molecular Modeling
Project Management
Peptides
Fragment Based Lead Discovery
Pharmaceutical Industry
Technology Transfer
Peptide Synthesis
Protein Chemistry
Nmr
Interests:
The Skyx Pro
Ccdsoft
5 Inch Apo Refractor
Astrophysics
Astrophotography (Deep Space)
90 Mm Apo Refractor
Software
Guitar
Imagesplus
Ccdops
Running Gemini
Mount
Scopes
Losmandy Titan
Focusmax
14 Inch Sct
Photoshop Cs6 Guitar
Phd Guiding
Lrgb and Narrow Band
O Iii
Photoshop Cs6
Ccdstack V 2
Maximdl
Jerry Skiles Photo 2

Medicinal Chemistry Consultant At Biopredict, Inc.

view source
Position:
Medicinal Chemistry Consultant at BioPredict, Inc.
Location:
Greater Boston Area
Industry:
Biotechnology
Work:
BioPredict, Inc. - Oradell, New Jersey since Aug 2011
Medicinal Chemistry Consultant

CytRx Corporation (RXi Pharmaceuticals) - Worcester, Ma Dec 2003 - Jun 2009
Director of Chemistry

Discovery Partners International - La Jolla, CA Jan 2001 - Dec 2003
Principal Scientist

Novartis - Summit, NJ Oct 1993 - Dec 2000
Research Fellow

Novartis - Summit, Ne Jersey 1992 - 2000
Research Fellow
Education:
Kent State University
BS, Chemistry
University of Pennsylvania
Ph.D., Organic Chemistry
Interests:
Additional interests outside of chemistry and biology. Astronomy, astrophotography (deep space), astrophysics, LRGB and narrow band (H-alpha, O-III, and S-II) imaging with dedicated astro-camera (SBIG ST-2000XM/CFW 10) and Canon 40D (modified) DSLR,SBIG St-i and Guider Kit. SBIG STT-8300M & FW8G Color Filter Wheel & Auto-Guider; Scopes: 14 inch SCT, 5 inch APO refractor, 90 mm APO refractor. Mount: Losmandy Titan (50:1) running Gemini. Software: The SkyX-pro, CCDSoft, MaximDL, FocusMax, ImagesPlus, CCDStack V 2.0, CCDOps, PhD Guiding, Photoshop CS6 Guitar
Honor & Awards:
Edgar Fahs Smith Research Fellow, Department of Chemistry (University of Pennsylvania) Chemistry Department's Annual Teaching Award (University of Pennsylvania) Chemistry Department's Busch Research Fellowship (University of Pennsylvania, awarded 2 years in a row) NIH Fellowship (University of Pennsylvania) Principal Investigator: National Institute of Diabetes and Digesitive and Kidney Diseases (NIDDK) SBIR Grant No.: 1 R43 DK074186-01A1

Classmates

Jerry Skiles Photo 3

Jerry Skiles Harrisburg ...

view source
Jerry Skiles 1972 graduate of Harrisburg High School in Harrisburg, OR is on Classmates.com. See pictures, plan your class reunion and get caught up with Jerry and other high ...
Jerry Skiles Photo 4

Jerry Skiles Ft. defianc...

view source
Jerry Skiles 1973 graduate of Window Rock High School in Ft. defiance, AZ is on Classmates.com. See pictures, plan your class reunion and get caught up with Jerry and other high ...
Jerry Skiles Photo 5

Jerry Skiles

view source
Schools:
Industry High School Industry IL 1956-1960
Community:
Byron Mcdaniel, Cheri Cutright, Phyllis O'keefe
Jerry Skiles Photo 6

Window Rock High School, ...

view source
Graduates:
Perphina Wauneka (1995-1999),
Fabian Yazzie (1993-1997),
Samantha Showalter (1996-2000),
Jerry Skiles (1969-1973),
Travis Yellowhair (1994-1998)
Jerry Skiles Photo 7

United Township High Scho...

view source
Graduates:
Edmundo Soliz (1972-1976),
Kim Crafton (1977-1981),
Jerry Skiles (1967-1971),
Dawn Ramos (1985-1989),
Dina Lentz (1986-1990)
Jerry Skiles Photo 8

Industry High School, Ind...

view source
Graduates:
Janice Armstrong (1972-1976),
Jerry Skiles (1956-1960),
Beryl Janes (1977-1981),
Rodney Wilson (1983-1987),
David Onion (1972-1976),
Elsie Skiles (1945-1949)
Jerry Skiles Photo 9

Harrisburg High School, H...

view source
Graduates:
Barbara Smith (1960-1965),
Melissa Carr (1990-1993),
Douglas Sullivan (1974-1978),
Thresa Haag (1974-1975),
Jerry Skiles (1968-1972)
Jerry Skiles Photo 10

Vidor High School, Vidor,...

view source
Graduates:
Timothy Sims (1984-1988),
Jerry Youngblood (1952-1956),
Holly Phelps (1989-1993),
Jerry Skiles (1960-1964),
Stephany Isaacs (1987-1991)

Googleplus

Jerry Skiles Photo 11

Jerry Skiles

Facebook

Jerry Skiles Photo 12

Jerry Skiles

view source
Friends:
Michael Welsh, Cam DePauw, Jeremy Thrasher, Rachel Levsen, Jeremy Hochstein

Youtube

Chicago Bulls White Sox Chair Jerry Reinsdorf...

In case you missed it on WGN TV's Instant Replay program, Chicago Bull...

  • Category:
    Sports
  • Uploaded:
    28 Jan, 2008
  • Duration:
    5m 52s

1982: Michigan-31 Michigan State-17

Game played on October 9, 1982 in Ann Arbor. 1982 Michigan Wolverines ...

  • Category:
    Sports
  • Uploaded:
    11 Dec, 2008
  • Duration:
    9m 56s

NBA 2k10 - Thunder (xMAGx iKiWIXEL) -vs- Bux ...

- Playlist - (1) Imogen Heap - 'Hide and Seek' (2) Aboriginals - 'Keep...

  • Category:
    Gaming
  • Uploaded:
    09 Sep, 2010
  • Duration:
    12m 33s

NBA 2k10 - Cavs (KINGcavs23) -vs- Bux (boltok...

- Playlist - (1) Mystikal - 'The Man Right Chea' (2) Brotherman - 'Sla...

  • Category:
    Gaming
  • Uploaded:
    09 Sep, 2010
  • Duration:
    14m 55s

7 - 24 - 22 Healing Is Here - Jerry Skiles

Personal testimony of Jerry Skiles. Hear his journey of discovering Go...

  • Duration:
    20m 37s

Jerry of the Day Best of 2020

2020: The year that all odds were against Jerry. It can be hard to kee...

  • Duration:
    6m 47s

How Great Thou Art

My take on a classic.

  • Duration:
    4m 2s

I Just Want To Thank You, Lord

Original Christian Music.

  • Duration:
    4m 41s

Get Report for Jerry W Skiles from Berlin, MA, age ~76
Control profile