In S Kim

US Patent:

6680027, Jan 20, 2004

Filed:

Jul 30, 2001

Appl. No.:

09/918288

Inventors:

Jemo Kang - Princeton NJ
Kyung-ah Kim - Princeton NJ
Arthur Weber - Whitehouse Station NJ
In Jung Kim - West Windsor NJ
Larry Porter - Princeton NJ
Won Bae Yoon - Plainsboro NJ

Assignee:

Princeton BioMeditech Corporation - Monmouth Junction NJ

International Classification:

G01N 2100

US Classification:

422 58, 422 56, 422 61, 422 63, 422 681, 422100, 422102, 422103, 422104, 436165, 436178

Abstract:

A collection and testing cup for fluid characterization is disclosed. The cup has a lid assembly with a tamper evident closure; a cylinder that extends into the fluid in the collection cup, also with a tamper evident closure; a piston with a conduit and one-way valve through which a portion of the fluid can be forced into an isolation chamber separate from the main collection cup for testing. The lid assembly cylinder is configured with an aperture or passage near the bottom of the cylinder to allow a small portion of fluid to enter the lower portion of the cylinder from the collection cup chamber and a piston with a central conduit and valve initially positioned near the top of the cylinder adjacent to the lid. The piston, when pushed down the cylinder, closes the aperture communicating with collection cup chamber and forces a predetermined volume of fluid from the lower portion of the cylinder through the conduit and valve to the upper portion of the cylinder, isolating a portion of the fluid sample from the fluid in the collection cup chamber. The valve prevents the fluid from returning to the lower portion of the cylinder and to the collection cup chamber.

US Patent:

7470404, Dec 30, 2008

Filed:

Jan 5, 2004

Appl. No.:

10/751797

Inventors:

Jemo Kang - Princeton NJ, US
Kyung-ah Kim - Princeton NJ, US
Arthur Weber - Whitehouse Station NJ, US
In Jung Kim - West Windsor NJ, US
Larry Porter - Princeton NJ, US
Won Bae Yoon - Plainsboro NJ, US

Assignee:

Princeton Biomeditech Corporation - Princeton NJ

International Classification:

G01N 33/00

US Classification:

422102, 422 50, 422 55, 422 56, 422 57, 422 58, 422 681, 422 99, 422100, 422103

Abstract:

A collection and testing cup for fluid characterization is disclosed. The cup has a lid assembly with a tamper evident closure; a cylinder that extends into the fluid in the collection cup, also with a tamper evident closure; a piston with a conduit and one-way valve through which a portion of the fluid can be forced into an isolation chamber separate from the main collection cup for testing. The lid assembly cylinder is configured with an aperture or passage near the bottom of the cylinder to allow a small portion of fluid to enter the lower portion of the cylinder from the collection cup chamber and a piston with a central conduit and valve initially positioned near the top of the cylinder adjacent to the lid. The piston, when pushed down the cylinder, closes the aperture communicating with collection cup chamber and forces a predetermined volume of fluid from the lower portion of the cylinder through the conduit and valve to the upper portion of the cylinder, isolating a portion of the fluid sample from the fluid in the collection cup chamber. The valve prevents the fluid from returning to the lower portion of the cylinder and to the collection cup chamber.

US Patent:

20130317027, Nov 28, 2013

Filed:

Dec 7, 2012

Appl. No.:

13/708235

Inventors:

Jeffrey W. Lockman - Princeton Junction NJ, US
Brett R. Murphy - Collbran CO, US
Weston R. Judd - Farmington UT, US
In Chul Kim - Louisville KY, US
Se-Ho Kim - Salt Lake City UT, US
Daniel Feodore Zigar - Salt Lake City UT, US
Kraig M. Yager - Murray UT, US
Tracey C. Fleischer - Sandy UT, US
Ryan T. Terry-Lorenzo - Marlborough MA, US
J. Jay Boniface - Salt Lake City UT, US
Daniel P. Parker - Sandy UT, US
Ian A. McAlexander - Salt Lake City UT, US
Matthew Gregory Bursavich - Needham MA, US
David M. Dastrup - Columbus OH, US
Christophe Hoarau - Pleasant Hill CA, US
David A. Gerrish - Lakewood OH, US
Paul R. Sebahar - Sandy UT, US
Dange Vijay Kumar - Salt Lake City UT, US

Assignee:

Myrexis, Inc. - Salt Lake City UT

International Classification:

C07D 213/46
C07D 295/135
C07D 235/06
C07D 401/12

US Classification:

5142355, 546332, 514357, 546261, 514335, 5462754, 514341, 546194, 514318, 546265, 514332, 5483044, 514394, 5462764, 514343, 5462727, 544284, 51426621, 544360, 435375, 51425301, 544131

Abstract:

The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.

US Patent:

20230115580, Apr 13, 2023

Filed:

Apr 13, 2022

Appl. No.:

17/720079

Inventors:

- Watertown MA, US
Jianming Yu - Plainsboro NJ, US
Kevin McGrath - Brighton MA, US
Xiben Li - Lexington MA, US
Tyler J. Mann - Brighton MA, US
Robert Leon - Sharon MA, US
In Jong Kim - Lexington MA, US
Yat Sun Or - Waltham MA, US
Long Nguyen - Boston MA, US

International Classification:

C07D 491/048
C07D 519/00
A61K 45/06

Abstract:

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

US Patent:

20230108803, Apr 6, 2023

Filed:

Feb 24, 2022

Appl. No.:

17/679746

Inventors:

- Watertown MA, US
Jianming Yu - Plainsboro NJ, US
Kevin McGRATH - Brighton MA, US
Xiben Li - Lexington MA, US
Tyler J. Mann - Brighton MA, US
Robert Leon - Sharon MA, US
In Jong Kim - Lexington MA, US
Yat Sun Or - Waltham MA, US
Long Nguyen - Boston MA, US

International Classification:

C07F 9/09
C07D 491/048
C07D 519/00
A61K 45/06

Abstract:

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

US Patent:

20200323872, Oct 15, 2020

Filed:

Apr 7, 2020

Appl. No.:

16/842539

Inventors:

- WATERTOWN MA, US
Jianming Yu - Plainsboro NJ, US
In Jong Kim - Lexington MA, US

International Classification:

A61K 31/55
A61K 45/06
C07D 491/107
A61P 31/14

Abstract:

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.