Harry Fein

US Patent:

6749834, Jun 15, 2004

Filed:

Jun 19, 2001

Appl. No.:

09/884786

Inventors:

Harry Fein - Nokomis FL
Xueji Zhang - Sarasota FL

Assignee:

World Precision Instruments, Inc. - Sarasota FL

International Classification:

A61L 904

US Classification:

424 45, 424 43, 424600, 424718, 12820011, 12820012, 12820024, 514958

Abstract:

A storage and delivery system for directly applying nitric oxide to a user includes a portable and disposable capsule and a source of nitric oxide gas disposed within the cavity. Gas flow control apparatus controls the flow of nitric oxide gas from the cavity. Gas flow initiation apparatus allows the user to initiate the flow of nitric oxide gas. The encapsulated nitric oxide gas is applied by positioning the capsule proximate to the objective site of the user and initiating flow of the nitric oxide gas.

US Patent:

20040197274, Oct 7, 2004

Filed:

Apr 27, 2004

Appl. No.:

10/833182

Inventors:

Harry Fein - Nokomis FL, US
Xueji Zhang - Sarasota FL, US

International Classification:

A61L009/04
A61M011/00
A61K033/00

US Classification:

424/045000, 424/718000, 128/200230

Abstract:

A storage and delivery system for directly applying nitric oxide to a user includes a portable and disposable capsule and a source of nitric oxide gas disposed within the cavity. Gas flow control apparatus controls the flow of nitric oxide gas from the cavity. Gas flow initiation apparatus allows the user to initiate the flow of nitric oxide gas. The encapsulated nitric oxide gas is applied by positioning the capsule proximate to the objective site of the user and initiating flow of the nitric oxide gas.

US Patent:

20120096955, Apr 26, 2012

Filed:

Oct 21, 2011

Appl. No.:

13/278562

Inventors:

Konrad Güth - Heidelberg, GE
Harm J. Knot - Haren, NE
Harry Fein - Nokomis FL, US

Assignee:

WORLD PRECISION INSTRUMENTS, INC. - Sarasota FL

International Classification:

G01L 1/10

US Classification:

7386259

Abstract:

The scientific characterization of cellular contractility and cell movement, such as muscle function in particular is, to a large extent, carried out on intact tissue preparations for example using whole intact muscles from animals. Typical indices of muscle function may include isometric force, contractility under external force (load) and spatio-temporal determination of internal calcium concentration under strictly controlled conditions of length and applied force. The major advance of the described apparatus is that the common characterization of cellular contractility can be performed on a single cell rather than an entire tissue or whole animal. As such the apparatus described improves on and eliminates known limitations of currently considered state-of-the-art approaches.

US Patent:

49120603, Mar 27, 1990

Filed:

Feb 17, 1989

Appl. No.:

7/312043

Inventors:

Harry Fein - Guilford CT

Assignee:

World Precision Instruments, Inc. - New Haven CT

International Classification:

C12M 134

US Classification:

435291

Abstract:

A method and apparatus for electrical testing of membrane tissue employs a pair of rack sections which have cavities for receiving opposing end portions of the culture cup. The culture cup and rack sections are clamped together to form test chambers at opposing sides of the cup substrate on which the experimental tissue is grown. Electrode cartridges are inserted into axial bores of the receiving cavities to provide a test current through the membrane tissue. Integral connectors connect with conduits for passing irrigation streams through the test chambers.

US Patent:

60163720, Jan 18, 2000

Filed:

Apr 6, 1998

Appl. No.:

9/055865

Inventors:

Harry Fein - Venice FL
Su-Yi Liu - Sarasota FL

Assignee:

World Precision Instruments, Inc. - Sarasota FL

International Classification:

G02B 620

US Classification:

385 12

Abstract:

A gas or vapor permeable optical fiber waveguide with a liquid core is employed as a probe for the detection or measurement of a chemical specie of interest by filling the waveguide core region with a reagent liquid which undergoes a change in an optical characteristic thereof when exposed to the chemical specie and then inserting the filled waveguide into an environment in which the chemical specie may be present. The chemical specie, if present, will permeate through the waveguide wall and react with or be absorbed in the core liquid. Sensitivity is enhanced by controlling the pressure differential across the waveguide wall and/or by shaping the waveguide to enlarge the surface area. When the reaction generates light, the devices which detect that light will be shaped and disposed to maximize the collection thereof.

US Patent:

61044857, Aug 15, 2000

Filed:

Oct 7, 1998

Appl. No.:

9/167753

Inventors:

Rong Wang - Sarasota FL
Harry Fein - Nokomis FL

Assignee:

World Precision Instruments, Inc. - Sarasota FL

International Classification:

G01N 110

US Classification:

356246

Abstract:

Fluid samples of very small but precisely equal volume are repetitively collected and subsequently analyzed by being illuminated with measurement light. The collection cells fill spontaneously and the analysis is performed with the sample in the cell.

US Patent:

56363036, Jun 3, 1997

Filed:

Dec 18, 1995

Appl. No.:

8/574359

Inventors:

Diping Che - Sarasota FL
Harry Fein - Venice FL

Assignee:

World Precision Instruments, Inc. - Sarasota FL

International Classification:

G02B 632

US Classification:

385 33

Abstract:

A chromatically variable light source includes a plurality of light emitting diodes which generate substantially monochromatic light at different wavelengths. The light source includes circuitry for selectively energizing one or more of the light emitting diodes and for controlling the intensity of the generated light. The light generated by the light emitting diodes is combined in a single light pipe and delivered to an output port for use.