George Vratsanos - Yardley PA, US Jean-Claude Becker - Princeton NJ, US Michael Corbo - Flemington NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 38/16
US Classification:
514 12
Abstract:
The invention relates to methods and compositions for treating undifferentiated arthritis (UA) and/or preventing the development of rheumatoid arthritis (RA) in subjects with UA by administering to a subject in need thereof an effective amount of soluble CTLA4 molecule.
Method For Retarding Progression To Definite Rheumatoid Arthritis In Subjects With Undifferentiated Arthritis
George Vratsanos - Yardley PA, US Jean-Claude Becker - Princeton NJ, US Michael Corbo - Flemington NJ, US
International Classification:
A61K 38/17 A61K 39/395
US Classification:
514 212, 4241341
Abstract:
The invention relates to methods and compositions for treating undifferentiated arthritis (UA) and/or preventing the development of rheumatoid arthritis (RA) in subjects with UA by administering to a subject in need thereof an effective amount of soluble CTLA4 molecule.
Method Of Vaccinating Subjects Receiving Immune Modulating Therapy
George Vratsanos - Yardley PA, US Francisco Leon - Bethesda MD, US Lee Tay - Princeton Junction NJ, US Kenneth Bahrt - Edison NJ, US
International Classification:
A61K 39/145 A61K 39/02 A61P 31/16
US Classification:
424209100, 424236100, 424244100
Abstract:
The present invention relates to methods of vaccinating subjects receiving immune modulating therapy, such as soluble CTLA4 molecules, for treatment of immune system diseases mediated by T-cell interactions with B7-positive cells including, but not limited to, autoimmune diseases, immunoproliferative diseases, and immune disorders associated with graft transplantation.
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