George A Komatsoulis

US Patent:

6476195, Nov 5, 2002

Filed:

Jan 24, 2000

Appl. No.:

09/489847

Inventors:

George Komatsoulis - Silver Spring MD
Craig A. Rosen - Laytonsville MD
Steven M. Ruben - Olney MD
Roxanne D. Duan - Bethesda MD
Paul A. Moore - Germantown MD
Yanggu Shi - Gaithersburg MD
David W. LaFleur - Washington DC
Ying-Fei Wei - Berkeley CA
Jian Ni - Rockville MD
Kimberly A. Florence - Rockville MD
Paul Young - Gaithersburg MD
Laurie A. Brewer - St. Paul MN
Daniel R. Soppet - Centreville VA
Gregory A. Endress - Potomac MD
Reinhard Ebner - Gaithersburg MD
Henrik Olsen - Gaithersburg MD
Michael Mucenski - Cincinnati OH

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K 500

US Classification:

530350, 435 6, 435 71, 536 231

Abstract:

The present invention relates to novel human secreted protein (HNFGF20). Polypeptides of the invention are duseful in dianosis and treatment of disorders affecting the immune system.

US Patent:

6566325, May 20, 2003

Filed:

Jul 16, 2001

Appl. No.:

09/904615

Inventors:

Paul A. Moore - Germantown MD
Steven M. Ruben - Olney MD
Henrik S. Olsen - Gaithersburg MD
Yanggu Shi - Gaithersburg MD
Craig A. Rosen - Laytonsville MD
Kimberly A. Florence - Rockville MD
Daniel R. Soppet - Centreville VA
David W. LaFleur - Washington DC
Gregory A. Endress - Potomac MD
Reinhard Ebner - Gaithersburg MD
George Komatsoulis - Silver Spring MD
Roxanne D. Duan - Bethesda MD

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K 1400

US Classification:

514 2, 530350, 530300

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

US Patent:

6534631, Mar 18, 2003

Filed:

Jan 13, 2000

Appl. No.:

09/482273

Inventors:

Steven M. Ruben - Olney MD
George Komatsoulis - Silver Spring MD
Roxanne D. Duan - Bethesda MD
Craig A. Rosen - Laytonsville MD
Paul A. Moore - Germantown MD
Yanggu Shi - Gaithersburg MD
David W. LaFleur - Washington DC
Reinhard Ebner - Gaithersburg MD
Henrik Olsen - Gaithersburg MD
Laurie A. Brewer - St. Paul MN
Kimberly A. Florence - Rockville MD
Paul Young - Gaithersburg MD
Michael Mucenski - Cincinnati OH
Gregory A. Endress - Potomac MD
Daniel R. Soppet - Centreville VA

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K 1100

US Classification:

530350, 536 231, 536 241, 4353201, 435325, 530300

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

US Patent:

6605592, Aug 12, 2003

Filed:

Mar 8, 2001

Appl. No.:

09/800729

Inventors:

Jian Ni - Germantown MD
Kevin P. Baker - Darnestown MD
Charles E. Birse - North Potomac MD
Reinhard Ebner - Gaithersburg MD
Michele Fiscella - Bethesda MD
George A. Komatsoulis - Silver Spring MD
David W. LaFleur - Washington DC
Paul A. Moore - Germantown MD
Henrik S. Olsen - Gaithersburg MD
Craig A. Rosen - Laytonsville MD
Steven M. Ruben - Olney MD
Daniel R. Soppet - Centreville VA
Paul E. Young - Gaithersburg MD
Ping Wei - Brookeville MD
Kimberly A. Florence - Rockville MD

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K 1447

US Classification:

514 2, 530350, 514 8, 514 12, 435 691, 435 711, 435 712, 435471, 435325, 4352523, 43525411, 4353201

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. In particular, the present application relates to a novel human protein, Protein HOFNF53. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

US Patent:

6627741, Sep 30, 2003

Filed:

Dec 12, 2001

Appl. No.:

10/012542

Inventors:

Steven M. Ruben - Olney MD
Jian Ni - Germantown MD
Craig A. Rosen - Laytonsville MD
Ying-Fei Wei - Berkeley CA
Paul Young - Gaithersburg MD
Kimberly Florence - Rockville MD
Daniel R. Soppet - Centreville VA
Laurie A. Brewer - St. Paul MN
Gregory A. Endress - Florence MA
Kenneth C. Carter - North Potomac MD
Michael Mucenski - Cincinnati OH
Reinhard Ebner - Gaithersburg MD
David W. LaFleur - Washington DC
Henrik Olsen - Gaithersburg MD
Yanggu Shi - Gaithersburg MD
Paul A. Moore - Germantown MD
George Komatsoulis - Silver Spring MD

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K 1624

US Classification:

5303892, 5303871, 5303873, 5303877, 5303881, 53038815, 5303879, 5303891

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

US Patent:

6878687, Apr 12, 2005

Filed:

Jul 20, 2000

Appl. No.:

09/621011

Inventors:

Steven M. Ruben - Brookeville MD, US
Craig A. Rosen - Laytonsville MD, US
George Komatsoulis - Silver Spring MD, US
Yanggu Shi - Gaithersburg MD, US

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

A61K038/00
C07K014/00
C07H021/04

US Classification:

514 12, 514 2, 530350, 5303871, 536 231, 435 691, 435 697, 4352523, 4353201, 435325, 435366

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

US Patent:

6936691, Aug 30, 2005

Filed:

Apr 11, 2001

Appl. No.:

09/832129

Inventors:

Michele Fiscella - Bethesda MD, US
Ping Wei - Brookeville MD, US
David W. LaFleur - Washington DC, US
Henrik S. Olsen - Gaithersburg MD, US
Kevin P. Baker - Darnestown MD, US
Reinhard Ebner - Gaithersburg MD, US
George A. Komatsoulis - Silver Spring MD, US
Craig A. Rosen - Laytonsville MD, US
Steven M. Ruben - Olney MD, US
Roxanne D. Duan - Bethesda MD, US
Paul E. Young - Gaithersburg MD, US
Kimberly A. Florence - Rockville MD, US
Paul A. Moore - Germantown MD, US
Charles E. Birse - Potomac MD, US
Jian Ni - Rockville MD, US
Daniel R. Soppet - Centreville VA, US
Yanggu Shi - Gaithersburg MD, US

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

C07K001/00

US Classification:

530350, 530300, 5303871, 435 71, 435 4, 435 6, 435 691

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

US Patent:

6953667, Oct 11, 2005

Filed:

Jan 25, 2002

Appl. No.:

10/054988

Inventors:

Paul A. Moore - Germantown MD, US
Steven M. Ruben - Olney MD, US
Henrik S. Olsen - Gaithersburg MD, US
Yanggu Shi - Gaithersburg MD, US
Craig A. Rosen - Laytonsville MD, US
Kimberly A. Florence - Rockville MD, US
Daniel R. Soppet - Centreville VA, US
David W. LaFleur - Washington DC, US
Gregory A. Endress - Potomac MD, US
Reinhard Ebner - Gaithersburg MD, US
George Komatsoulis - Silver Spring MD, US
Roxanne D. Duan - Bethesda MD, US

Assignee:

Human Genome Sciences, Inc. - Rockville MD

International Classification:

G01N033/53
C12N009/96
C07K016/22
C07K017/02

US Classification:

435 71, 435188, 5303879, 53038825, 5303893, 5303873, 5303913, 5303915

Abstract:

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.