Gavreel F Kalantarov from 2215 N Central Rd #3C, West Fort Lee, NJ 07024, age 64, Phone: 201-592-0950

Frozen Cell And Tissue Microarrays
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US Patent:

20100323907, Dec 23, 2010
Filed:

Oct 27, 2006
Appl. No.:

12/446575
Inventors:

Long Ai Ton-That - Bronx NY, US
Gavreel Kalantarov - Fort Lee NJ, US
Ilya Trakht - Bronx NY, US
International Classification:

C40B 30/04
C12N 5/071
G01N 33/53
C12Q 1/68
C40B 50/06
C40B 40/02
US Classification:

506 9, 435404, 435395, 435 71, 435 792, 435 6, 506 26, 506 14
Abstract:

The invention is directed to a new composition for making a housing block for cryosectioning comprising agarose and optimal cutting temperature medium. The invention is further directed to new methods for making a frozen section microarray of fresh non-fixed frozen cell or tissue samples that undergo only one freeze-thaw cycle before being used in a biological assay.

Anti-Drug Vaccines
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US Patent:

20120269828, Oct 25, 2012
Filed:

Apr 20, 2012
Appl. No.:

13/452019
Inventors:

Donald W. Landry - New York NY, US
Gavreel Kalantarov - Fort Lee NJ, US
Assignee:

The Trustees of Columbia University in the City of New York - New York NY
International Classification:

A61K 39/385
A61P 37/04
A61K 39/44
A61P 25/30
C07D 451/12
C07K 17/02
US Classification:

4241781, 4241931, 546130, 546131, 530363, 5303917
Abstract:

The present invention relates to anti-drug vaccines based on conjugates between the drug and a non-immunogenic carrier protein. In preferred embodiments, it provides for anti-cocaine vaccines and their use to diminish the effects and/or use of cocaine in a subject.

Fully Human Hybridoma Fusion Partner Cell Lines
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US Patent:

20070141064, Jun 21, 2007
Filed:

Aug 25, 2006
Appl. No.:

11/510490
Inventors:

Ilya Trakht - Bronx NY, US
Gavreel Kalantarov - Fort Lee NJ, US
International Classification:

A61K 39/395
C07H 21/04
C12P 21/06
C12N 5/06
C07K 14/82
C07K 16/30
US Classification:

424155100, 530350000, 530388800, 435069100, 435338000, 536023530
Abstract:

Certain aspects of the present invention are directed to new fully human fusion partner cell lines called human Karyochi cells, and to methods for making them. Human Karyochi cells are then fused with human antibody-secreting lymphoid cells to make fully human hybridomas called Karyochi-based hybridomas, which likewise secrete fully human monoclonal antibodies. Human Karyochi cells are made by isolating a donor nucleus that is substantially free of cytoplasm from either a first malignant B-lymphocyte cell line or a normal B-lymphocyte, and transferring the donor nucleus into the cytoplasm of a recipient cell from a second T- or B-lymphoid cell line. With time the nuclei synchronize and fuse to form the chimeric Karyochi fusion partner cell line. Nuclear transfer can be accomplished using intra-cytosolic nucleus injection or by impact-induced nucleus administration.

Development Of Dual Whole Cell-Based Vaccine Against Pancreatic Cancer
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US Patent:

20190083590, Mar 21, 2019
Filed:

Mar 3, 2017
Appl. No.:

16/082184
Inventors:

Gavreel KALANTAROV - Fort Lee NJ, US
Ilya TRAKHT - Bronx NY, US
International Classification:

A61K 39/00
A61K 9/00
C12N 5/0784
Abstract:

Disclosed herein is a different and novel approach to cancer vaccines using a subject's own dendritic cells (DCs) and macrophages (Mphs) in combination to present cancer antigens to the immune system. Further disclosed are methods of producing monocyte-derived autologous DCs and Mphs loaded ex vivo with particular whole irradiated cancer cells which generates optimally activated immunostimulatory antigen-presenting cells (APCs) as a superior method for stimulating robust and long-lasting immunity to a particular cancer in vivo as compared with more traditional vaccination methods. Compositions, methods of use and methods for preparation of these DCs and Mphs with cancer cells are also disclosed herein.

Anti-Drug Vaccines
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US Patent:

20150343042, Dec 3, 2015
Filed:

Aug 14, 2015
Appl. No.:

14/827191
Inventors:

- New York NY, US
Donald W. Landry - New York NY, US
Gavreel Kalantarov - Fort Lee NJ, US
llya Trakht - Bronx NY, US
Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
International Classification:

A61K 39/00
A61K 39/385
Abstract:

The present invention relates to anti-drug vaccines based on conjugates between the drug and a non-immunogenic carrier protein. In preferred embodiments, it provides for anti-cocaine vaccines and their use to diminish the effects and/or use of cocaine in a subject.

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Gavreel F Kalantarov