Medical Education • Healthcare • Hospitals • Clinical Research • Medicine • Healthcare Management • Patient Safety • Public Health • Emr • Healthcare Information Technology
Languages
English
Awards
Healthgrades Honor Roll
Ranks
Certificate:
Emergency Medicine, 2010
Industries
Hospital & Health Care
Specialities
Emergency Medicine
Us Patents
Microfluidic Device For Size And Deformability Measurements And Applications Thereof
- Ann Arbor MI, US Alyse D. Krausz - Ann Arbor MI, US Sarah Elizabeth Mena - Ann Arbor MI, US Martin Patrick De Beer - Ann Arbor MI, US Kevin R. Ward - Superior Township MI, US Frederick Korley - Ann Arbor MI, US
A microfluidic device system includes a channel having an entrance and an exit, a height at the entrance being greater than a height at the exit. The height of the channel may decrease continuously from the height at the entrance to the height at the exit. Cells or particles or beads traveling through the channel become trapped based on their size and/or deformability. A visual sensor captures images of the trapped cells or particles or beads, and image software analyzes the captured images to provide size and/or deformability and/or fluorescence information. A method of fabricating such a microfluidic device includes introducing a glass wafer to an etching solution at a specific rate such that a first end of the glass wafer is etched longer than other portions of the glass wafer.
Multi-Protein Biomarker Assay For Brain Injury Detection And Outcome
- Baltimore MD, US Jennifer E. VAN EYK - Baltimore MD, US Frederick KORLEY - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
G01N 33/68 C12Q 1/6883
Abstract:
The present invention relates to the field of brain injuries. More specifically, the present invention provides methods and compositions useful in the diagnosis/prognosis/assessment of brain injuries. In a specific embodiment, a method for identifying which patients with traumatic brain injury (TBI) require a head computerized tomography (CT) scan for diagnosing acute intracranial pathology comprises the steps of (a) obtaining or collecting a sample from the patient; (b) measuring the levels of one or more biomarkers in the blood sample obtained from the patient, wherein the biomarkers comprise glial fibrillary acidic protein (GFAP), S100B, metallothionein 3 (MT3), neuron specific enolase (NSE) and intracellular adhesion molecule 5 (ICAM5); and (c) identifying the patient as requiring or not requiring a head CT scan based on the measured levels of one or more of biomarkers comprising GFAP, S100B, MT3, NSE and ICAM5.
Multi-Protein Biomarker Assay For Brain Injury Detection And Outcome
- Baltimore MD, US JENNIFER E. VAN EYK - BALTIMORE MD, US FREDERICK KORLEY - BALTIMORE MD, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
G01N 33/68 C12Q 1/6883
Abstract:
The present invention relates to the field of brain injuries. More specifically, the present invention provides methods and compositions useful in the diagnosis/prognosis/assessment of brain injuries. In a specific embodiment, a method for identifying which patients with traumatic brain injury (TBI) require a head computerized tomography (CT) scan for diagnosing acute intracranial pathology comprises the steps of (a) obtaining or collecting a sample from the patient; (b) measuring the levels of one or more biomarkers in the blood sample obtained from the patient, wherein the biomarkers comprise glial fibrillary acidic protein (GFAP), S100B, metallothionein 3 (MT3), neuron specific enolase (NSE) and intracellular adhesion molecule 5 (ICAM5); and (c) identifying the patient as requiring or not requiring a head CT scan based on the measured levels of one or more of biomarkers comprising GFAP, S100B, MT3, NSE and ICAM5.
Multi-Protein Biomarker Assay For Brain Injury Detection And Outcome
- Baltimore MD, US Jennifer E. Van Eyk - Los Angeles CA, US Frederick Korley - Fulton MD, US
International Classification:
G01N 33/68
Abstract:
The present invention relates to the field of brain injuries. More specifically, the present invention provides methods and compositions useful in the diagnosis/prognosis/assessment of brain injuries. In a specific embodiment, a method for identifying which patients with traumatic brain injury (TBI) require a head computerized tomography (CT) scan for diagnosing acute intracranial pathology comprises the steps of (a) obtaining or collecting a sample from the patient; (b) measuring the levels of one or more biomarkers in the blood sample obtained from the patient, wherein the biomarkers comprise glial fibrillary acidic protein (GFAP), S100B, metallothionein 3 (MT3), neuron specific enolase (NSE) and intracellular adhesion molecule 5 (ICAM5); and (c) identifying the patient as requiring or not requiring a head CT scan based on the measured levels of one or more of biomarkers comprising GFAP, S100B, MT3, NSE and ICAM5.
Johns Hopkins School of Medicine
Assistant Professor
Northwestern Memorial Hospital 2003 - 2007
Resident
University of Michigan 2003 - 2007
Associate Professor
Education:
Johns Hopkins Bloomberg School of Public Health 2010 - 2013
Doctorates, Doctor of Philosophy, Philosophy
Northwestern University - the Feinberg School of Medicine 1999 - 2003
Doctor of Medicine, Doctorates, Medicine
Morris Brown College 1996 - 1999
Bachelors, Bachelor of Science, Biology
Skills:
Medical Education Healthcare Hospitals Clinical Research Medicine Healthcare Management Patient Safety Public Health Emr Healthcare Information Technology
Medicine Doctors
Dr. Frederick K Korley, Baltimore MD - MD (Doctor of Medicine)