True Health Diagnostics Feb 2016 - May 2017
Senior Vice President of New Product Strategy
Neomark Ventures Feb 2016 - May 2017
President
Metabolon, Inc. Oct 2011 - Aug 2015
Senior Vice President Diagnostics
Glycomark 2004 - 2011
President and Founder
Amplistar 1999 - 2003
President and Founder
Education:
The University of British Columbia 1987
Master of Science, Masters, Genetics
University of North Carolina at Greensboro
Skills:
Commercialization Biotechnology Medical Devices Technology Transfer Cross Functional Team Leadership Glp Licensing Clinical Research Fda Validation Product Development R&D Biomarkers Strategy Venture Capital Clinical Trials Drug Discovery Global Strategy Development Business Development Marketing Early Stage Startups Turnaround Initiatives Ipo Regulatory Compliance Fda Approval Board Relations Investor Relations Emerging Technologies Strategic Alliances Kol Development Advisory Boards Board Governance Evaluating Strategic Intent/Portfolio Viability/Patentability Senior Executive Leadership Creating Shareholder Value Investor Liaison Positioning Companies For Profitable Sale Board of Directors Addressing Unmet Diagnostic Needs Driving Product Innovation Patents Regulatory Compliance/Fda Approval Scientific/Clinical Advisory Boards Group Presentations Engaging Thought Leaders Advising Executive Leaders Joint Ventures Strategic Partnerships Board Development Mergers and Acquisitions
1,5-Anhydroglucitol (1,5-Ag) Assay And A1C/1,5-Ag Assay Combination For Measuring Blood Glucose Excursions In General And Postprandial Hyperglycemia In Diabetic Patients
John B. Buse - Chapel Hill NC, US Kathleen Dungan - Durham NC, US Steven D. Wittlin - Rochester NY, US Eric A. Button - Kannapolis NC, US Shuhei Kato - Tokyo, JP Toshio Tanabe - Tokyo, JP
Assignee:
Nippon Kayaku Kabushiki Kisha - Tokyo Toyota Tsusho America Inc. - New York NY
International Classification:
C12Q 1/54 C12M 1/00
US Classification:
435 14, 4352871
Abstract:
The invention is a method of measuring blood glucose excursions in general, and postprandial hyperglycemia in diabetic patients in particular, by the 1,5-anhydroglucitol assay (1,5-AG) or A1C/1,5-AG assay combination. 1,5-AG levels and percent changes of 1,5-AG levels in short period are indicative of differing postmeal glucose levels in moderately-controlled diabetic patients with similar A1C levels. Thereby 1,5-AG assay is useful to identify diabetic patients who may be at risk for cardiovascular complications which would not be identifiable by A1C levels alone. Furthermore, ratios of A1C divided by 1,5-AG in each patient are superior indicators to 1,5-AG levels.
Identification Of Pre-Diabetes Using A Combination Of Mean Glucose And 1,5-Anhydroglucitol Markers
Eric A. Button - Cary NC, US Robert Scott Foster - Charleston SC, US
International Classification:
C12Q 1/54
US Classification:
435 14
Abstract:
Described herein is a method for determining the disease state in a patient using combined mean glucose measurements and 1,5-anhydroglucitol to identify individuals at risk for developing diabetes. The ratio of mean glucose measurements to 1,5-anhydroglucitol correlates significantly better to maximal levels of postmeal glucose levels and related measurements, than mean glucose measurements or 1,5-anhydroglucitol correlate independently.