Richard I. Brown - Northbrook IL Sidney Smith - Lake Forest IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 2126
US Classification:
210789, 210782, 210787, 435 2, 494 37
Abstract:
A method of processing blood establishes communication between a donor and a blood flow path and pumps whole blood from the donor into a container through the blood flow path. The method centrifugally separates the whole blood in the container into concentrated red blood cells and a plasma constituent. After the method interrupts communication between the donor and the blood flow path, the method pumps the concentrated red blood cells from the container to mix the concentrated red blood cells with a nutritive solution to restore the hematocrit of the concentrated red blood cells to a desired value. The method also removes the plasma constituent.
Centrifugation System Having An Interface Detection Surface
Richard I. Brown - Northbrook IL Sidney Smith - Lake Forest IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 3300 B01D 2126
US Classification:
210 85
Abstract:
A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
Richard I. Brown - Northbrook IL Sidney Smith - Lake Forest IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 2126 B04B 700 B04B 708
US Classification:
2103601
Abstract:
A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
David Bacehowski - Wildwood IL David Cerny - Lilburn GA Dean Glash - McHenry IL Richard Afflerbaugh - Libertyville IL Joseph West - LakeVilla IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
A61B 1900
US Classification:
604408
Abstract:
An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.
Richard I. Brown - Northbrook IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL Joseph C. West - Fox Lake IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 2126
US Classification:
210369
Abstract:
An apparatus and method of separating a component from a collected quantity of fluid. The apparatus includes a dual member centrifuge and an associated fluid flow transfer set. The transfer set has a collection container in which a quantity of fluid can be initially accumulated. The collection container is formed as a disk-shaped plastic member with an elongated generally radially extending barrier member formed therein. A component collection container is in fluid flow communication with the disk-shaped container. The method provides for centrifugation of the collection container in the dual member centrifuge thereby separating out the selected fluid component. The component can then be pumped out of the collection container into the component accumulation container. The residual fluid can be sealed in the collection container for later use. The component collection container can be separated and sealed also for later use.
Centrifugation Chamber Having An Interface Detection Surface
Richard J. Brown - Northbrook IL Sidney Smith - Lake Forest IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 2126
US Classification:
210 94
Abstract:
A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
Richard I. Brown - Northbrook IL Sidney Smith - Lake Forest IL David E. Cerny - Crystal Lake IL John T. Foley - Wheeling IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 2126 A61M 138
US Classification:
210782
Abstract:
A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
David E. Cerny - Crystal Lake IL David V. Bacehowski - Wildwood IL
Assignee:
Baxter Travenol Laboratories, Inc. - Deerfield IL
International Classification:
A61B 1900
US Classification:
604406
Abstract:
A fluid collection system includes an input unit having a hollow needle coupled through a section of flexible conduit to an anticoagulant reservoir which is in turn coupled via a second section of hollow conduit to a first sterile connector. A collection container, which can be a dry, flexible, plastic bag, is coupled by a plastic conduit to second and third sterile connectors. The first and second connectors can be joined together and sealed to form a sterile system. A transfer container includes a flexible plastic container coupled via a hollow plastic conduit to a fourth sterile connector. The fourth sterile connector is joinable with the third sterile connector to form a sterile two container system. Fluids collected in the primary container can then be transferred to the secondary container.