Daniel P Gestwick

US Patent:

20110203688, Aug 25, 2011

Filed:

Nov 17, 2010

Appl. No.:

12/948566

Inventors:

Michael W. Reed - Lake Forest Park WA, US
Oliver Z. Nanassy - Edmonds WA, US
Paul V. Haydock - Shoreline WA, US
Daniel P. Gestwick - Seattle WA, US

Assignee:

BLOOD CELL STORAGE, INC. - Seattle WA

International Classification:

F04B 49/00
C07H 21/00
C12P 19/34
C07H 21/04
B65D 71/00

US Classification:

13756511, 536 2541, 435 915, 206223

Abstract:

Processes for extracting nucleic acid from a biological sample and related assemblies and kits are disclosed. The processes comprise the steps of (a) providing a device comprising an inner surface, an outer surface, a first port, and a second port, wherein the inner surface is composed of unmodified, smooth glass and defines a tubular lumen providing fluid communication between the first port and second port, wherein the lumen is circular, oval, or elliptical in cross-section, and wherein the lumen is essentially free of nucleic acid-specific binding sites; (b) introducing a nucleic acid-containing sample into the lumen of the device via the first port; (c) allowing nucleic acid in the sample to bind to the unmodified smooth glass surface; and (d) washing the bound nucleic acid.

US Patent:

20120296075, Nov 22, 2012

Filed:

May 18, 2012

Appl. No.:

13/475702

Inventors:

Michael W. Reed - Lake Forest Park WA, US
Daniel P. Gestwick - Seattle WA, US

Assignee:

BLOOD CELL STORAGE, INC. - Seattle WA

International Classification:

C07H 1/08
B01J 19/00
C07H 21/00

US Classification:

536 2541, 422129

Abstract:

A system, method, and kit for extracting nucleic acid from a sample containing nucleic acid uses an extraction device with an elongate channel. Fluids are provided to the channel via gravity feed to the inlet port. The flow rate and other flow behavior may be controlled with a siphon provided at the outlet port.