Cory Hargrove Janelle Cooke

US Patent:

7582431, Sep 1, 2009

Filed:

Nov 12, 2004

Appl. No.:

10/987549

Inventors:

Radoje Drmanac - Palo Alto CA, US
Snezana Drmanac - Palo Alto CA, US
David Kita - Foster City CA, US
Cory Cooke - San Mateo CA, US
Chongjun Xu - San Jose CA, US

Assignee:

Callida Genomics, Inc. - Sunnyvale CA

International Classification:

C12Q 1/68
C07H 21/04
C12P 19/34

US Classification:

435 6, 435 911, 435 9152, 536 231, 536 2432, 536 253

Abstract:

The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.

US Patent:

8034566, Oct 11, 2011

Filed:

Oct 30, 2007

Appl. No.:

11/929233

Inventors:

Radoje T. Drmanac - Palo Alto CA, US
Snezana Drmanac - Palo Alto CA, US
David Kita - San Mateo CA, US
Cory Cooke - San Mateo CA, US
Chongjun Xu - San Jose CA, US

Assignee:

Callida Genomics, Inc. - Sunnyvale CA

International Classification:

C12Q 1/68

US Classification:

435 611, 435 61

Abstract:

The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.

US Patent:

20110039731, Feb 17, 2011

Filed:

Dec 22, 2009

Appl. No.:

12/644860

Inventors:

Radoje Drmanac - Palo Alto CA, US
Snezana Drmanac - Palo Alto CA, US
David Kita - San Mateo CA, US
Cory Cooke - San Mateo CA, US
Chongjun Xu - San Jose CA, US

Assignee:

CALLIDA GENOMICS, INC. - Sunnyvale CA

International Classification:

C40B 40/06

US Classification:

506 16

Abstract:

The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and set of pools of probes, as well as method of generating pools of probes.

US Patent:

6864052, Mar 8, 2005

Filed:

Jan 6, 2000

Appl. No.:

09/479608

Inventors:

Radoje Drmanac - Palo Alto CA, US
Snezana Drmanac - Palo Alto CA, US
David Kita - Foster City CA, US
Cory Cooke - Newark CA, US
Chongjun Xu - San Jose CA, US

Assignee:

Callida Genomics, Inc. - Sunnyvale CA

International Classification:

C12Q001/68
C07H021/04
C07H021/02
C12P019/34

US Classification:

435 6, 435 911, 435 9152, 536 231, 536 2432, 536 253

Abstract:

The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.