Brent D Douty

Address:

3420 Strasburg Rd, East Fallowfield Township, PA 19320

VIN:

1G1AS18H797259497

Make:

Chevrolet

Model:

Cobalt

Year:

2009

US Patent:

53086074, May 3, 1994

Filed:

Feb 4, 1993

Appl. No.:

8/013605

Inventors:

Kurt A. Josef - Clifton Park NY
Edward R. Bacon - East Greenbush NY
Kimberly G. Estep - Albany NY
Carl R. Illig - Phoenixville PA
Brent D. Douty - Coatesville PA

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61K 4904
C07C 4500
C07C 4702

US Classification:

424 5

Abstract:

Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein R=C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR. sub. 1 R. sub. 2). sub. p --(CR. sub. 3. dbd. CR. sub. 4). sub. m Q, or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C--Q; R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are independently H, lower-alkyl, optionally substituted with halo; n is 1-5; m is 1-5; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.

US Patent:

53343700, Aug 2, 1994

Filed:

Feb 4, 1993

Appl. No.:

8/013459

Inventors:

Kurt A. Josef - Clifton Park NY
Edward R. Bacon - East Greenbush NY
Kimberly G. Estep - Albany NY
Carl R. Illig - Phoenixville PA
Brent D. Douty - Coatesville PA

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61K 4904
C07C 6976
C07C 2200
C07C 2500

US Classification:

424 5

Abstract:

Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology of the gastrointestinal tract wherein R=C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR. sub. 1 R. sub. 2). sub. p --(CR. sub. 3. dbd. CR. sub. 4). sub. m Q, or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C--Q; R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are independently H, lower-alkyl, optionally substituted with halo; n is 1-5; m is 1-5; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.

US Patent:

53728009, Dec 13, 1994

Filed:

Feb 4, 1994

Appl. No.:

8/192234

Inventors:

Edward R. Bacon - Rensselaer NY
Sol J. Daum - Albany NY
Kimberly G. Estep - Albany NY
Kurt A. Josef - Clifton Park PA
Brent D. Douty - Coatesville PA
Carl R. Illig - Phoenixville PA

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61K 4904

US Classification:

424 5

Abstract:

Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology of the gastrointestinal tract wherein X= ##STR2## Z=H, halo, C. sub. 1 -C. sub. 20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R=C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, aryl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, lower-alkoxy, hydroxy, carboxy or lower-alkoxy carbonyl, lower-alkenyl, lower-alkynyl, lower-alkylene or lower-alkoxy-carbonyloxy, n is 1-5; y is 0-4; and w is 1-4.

US Patent:

55103804, Apr 23, 1996

Filed:

Feb 19, 1993

Appl. No.:

8/019955

Inventors:

Peter R. Seoane - Coatesville PA
Joseph M. Salvino - Schwenksville PA
Brent D. Douty - Coatesville PA
Mohamed M. A. Awad - Frazer PA
Roland E. Dolle - King of Prussia PA
David G. Sawutz - Mohnton PA
David M. Faunce - Collegeville PA
Wayne T. Houck - Spring City PA

Assignee:

Sterling Winthrop, Inc. - New York NY

International Classification:

A61K 3116
C07C10330

US Classification:

514613

Abstract:

Disclosed are nonpeptides having bradykinin antagonist activity of the formulae (I) and (II) ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions containing the compound and methods of treating diseased or pathological conditions using the pharmaceutical compositions.

US Patent:

53857216, Jan 31, 1995

Filed:

Mar 22, 1994

Appl. No.:

8/217138

Inventors:

Edward J. Baker - Northumberland, GB2
Kurt A. Josef - Wayne PA
Edward R. Bacon - Audubon PA
Kimberly G. Estep - Pottstown PA
Carl R. Illig - Phoenixville PA
Brent D. Douty - Coatesville PA
John L. Toner - Downingtown PA
Robert W. Lee - Gilbertsville PA

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61K 4904
A61K 31715
A61K 3102

US Classification:

424 5

Abstract:

Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising an x-ray producing agent of the formula or a pharmaceutically acceptable salt thereof ##STR1## wherein R is methyl, ethyl, n-propyl, C. sub. 4 -C. sub. 25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, each of which may be optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy or lower-alkoxy carbonyl; (CR. sub. 1 R. sub. 2). sub. p --(CR. sub. 3. dbd. CR. sub. 4). sub. m Q, or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C--Q; R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are independently H, lower-alkyl, optionally substituted with halo; n is 2-5; m is 2-5; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl; in a pharmaceutically acceptable carrier comprising a cellulose derivative.

US Patent:

56206771, Apr 15, 1997

Filed:

Feb 1, 1994

Appl. No.:

8/189949

Inventors:

Carl R. Illig - Phoenixville PA
Eugene R. Cooper - Berwyn PA
John L. Toner - Downingtown PA
Donald A. Upson - West Chester PA
Brent D. Douty - Coatesville PA
Thomas J. Caulfield - Audubon PA
Edward R. Bacon - East Greenbush NY
Kimberly G. Estep - Albany NY
Kurt A. Josef - Clifton Park NY
Shaughnessy Robinson - Clifton Park NY
Paul P. Spara - Fairport NY

Assignee:

Sterling Winthrop Inc. - New York NY

International Classification:

A61K 4904

US Classification:

424 945

Abstract:

Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z=H, halo, C. sub. 1 -C. sub. 20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R=C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR. sub. 1 R. sub. 2). sub. p --(CR. sub. 3. dbd. CR. sub. 4). sub. m Q, or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C--Q; R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are independently lower-alkyl, optionally substituted with halo; x is 1-4; n is 1-5; m is 1-15; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.

US Patent:

53105389, May 10, 1994

Filed:

Mar 11, 1993

Appl. No.:

8/029484

Inventors:

Edward R. Bacon - East Greenbush NY
Carl R. Illig - Phoenixville PA
Thomas J. Caulfield - Audubon PA
Brent D. Douty - Coatesville PA
Kurt A. Josef - Clifton Park NY

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61K 4904
A61K 31275
A61K 3119
A61K 31075

US Classification:

424 5

Abstract:

##STR1## wherein Z=H, halo, C. sub. 1 -C. sub. 20 alkyl, cycloalkyl, lower alkoxy, alkoxycarbonyl, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R=C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, ##STR2## or halo-lower-alkyl, each of which may be optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR. sub. 1 R. sub. 2). sub. p --(CR. sub. 3 =CR. sub. 4). sub. m Q ,or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C--Q; R. sub. 1, R. sub. 2 and R. sub. 3 and R. sub. 4 are independently H, or lower-alkyl, optionally substituted with halo; x is 1-4; n is 1-4; m is 1-15; p is 1-20; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl These compounds are combined in a polymer for use as an X-ray contrast agent.

US Patent:

53487273, Sep 20, 1994

Filed:

Mar 11, 1993

Appl. No.:

8/029485

Inventors:

Edward R. Bacon - East Greenbush NY
Carl R. Illig - Phoenixville PA
Thomas J. Caulfield - Audubon PA
Brent D. Douty - Coatesville PA
Kurt A. Josef - Clifton Park NY

Assignee:

Sterling Winthrop Inc. - Malvern PA

International Classification:

A61B 5055
C07C 4100
A61K 31075

US Classification:

424 5

Abstract:

A compound of the formula: ##STR1## wherein Z. dbd. H, halo, C. sub. 1 -C. sub. 20 alkyl, cycloalkyl, lower alkoxy, alkoxycarbonyl, cyano, wherein thealkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R. dbd. C. sub. 1 -C. sub. 25 alkyl, cycloalkyl, ##STR2## or halo-lower-alkyl; each of which may be optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR. sub. 1 R. sub. 2). sub. p -(CR. sub. 3. dbd. CR. sub. 4). sub. m Q, or (CR. sub. 1 R. sub. 2). sub. p --C. tbd. C-Q; R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are independently H, or lower-alkyl, optionally substituted with halo; x is 1-4; n is [1-5]1-4; m is 1-15; p is 1-20; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, these compounds are useful as X-ray contrast agents or aryl-lower alkyl.