Binh Ha Pham

US Patent:

6535968, Mar 18, 2003

Filed:

May 1, 2001

Appl. No.:

09/847154

Inventors:

Binh Pham - Castro Valley CA

Assignee:

Sun Microsystems, Inc. - Santa Clara CA

International Classification:

G06F 1314

US Classification:

711167

Abstract:

An apparatus, system, and method for speeding up data transfers while reducing bus contention during repeated consecutive read-write operations. By reducing the length of time during which selected data pulses are driven on the memory bus, a higher percentage of usage of the memory bus may be attained without increasing the likelihood of bus contention and resulting degradation or damage to the memory system. The selected data pulse is preferably the write data pulse driven on the memory bus by the memory controller. A zero bus turnaround protocol may be implemented. The memory controller may include interface circuitry and write control circuitry that outputs an associated control signal to a three-state buffer. The three-state buffer, after being enabled by the associated control signal, drives write data on a data line of a memory bus. The turn-on delay associated with the three-state buffer exceeds the turn-off delay also associated with the three-state buffer.

US Patent:

7258873, Aug 21, 2007

Filed:

Apr 10, 2003

Appl. No.:

10/412651

Inventors:

Vu Truong-Le - Campbell CA, US
Binh Pham - Mountain View CA, US

Assignee:

MedImmune Vaccines, Inc. - Mountain View CA

International Classification:

A61K 9/14

US Classification:

424489, 424490, 424491, 424493, 424499

Abstract:

This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.

US Patent:

7700130, Apr 20, 2010

Filed:

May 31, 2007

Appl. No.:

11/809662

Inventors:

Vu Truong-Le - Campbell CA, US
Binh Pham - Mountain View CA, US

Assignee:

MedImmune LLC - Mountain View CA

International Classification:

A61K 9/14

US Classification:

424489, 424490, 424491, 424493, 424499

Abstract:

This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.

US Patent:

7923029, Apr 12, 2011

Filed:

Apr 10, 2003

Appl. No.:

10/412644

Inventors:

Vu Truong-Le - Campbell CA, US
Binh V. Pham - Mountain View CA, US
John F. Carpenter - Littleton CO, US
Robert Seid - Chapel Hill NC, US
Theodore W. Randolph - Niwot CO, US

Assignee:

MedImmune LLC - Gaithersburg MD

International Classification:

A61K 9/14
A61K 9/19

US Classification:

424489, 424491, 424492, 424493, 424497, 424499

Abstract:

This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles.

US Patent:

8012507, Sep 6, 2011

Filed:

Oct 29, 2007

Appl. No.:

11/978949

Inventors:

Vu Truong-Le - Campbell CA, US
Binh Pham - Mountain View CA, US

Assignee:

MedImmune Vaccines, Inc. - Mountain view CA

International Classification:

A61K 9/14
A61K 9/50

US Classification:

424489, 424490, 424491, 424493, 424499

Abstract:

This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.

US Patent:

8268354, Sep 18, 2012

Filed:

Nov 6, 2008

Appl. No.:

12/266493

Inventors:

Vu Truong-Le - Campbell CA, US
Satoshi Ohtake - Milpitas CA, US
Russell Andrew Martin - Los Gatos CA, US
Binh V. Pham - San Jose CA, US
Luisa Yee - Los Altos CA, US

Assignee:

Aridis Pharmaceuticals - San Jose CA

International Classification:

A61K 9/14
F26B 5/06

US Classification:

424489, 34293

Abstract:

This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles.

US Patent:

8273374, Sep 25, 2012

Filed:

Jul 29, 2011

Appl. No.:

13/194404

Inventors:

Vu Truong-Le - Campbell CA, US
Binh Pham - Mountain View CA, US

Assignee:

MedImmune, LLC - Gaithersburg MD

International Classification:

A61K 9/14
A61K 9/50

US Classification:

424489, 424490, 424491, 424493, 424499

Abstract:

This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.

US Patent:

8293275, Oct 23, 2012

Filed:

Sep 1, 2010

Appl. No.:

12/807343

Inventors:

Vu Truong-Le - Campbell CA, US
Binh V. Pham - Mountain View CA, US
John F. Carpenter - Littleton CO, US
Theodore W. Randolph - Niwot CO, US
Robert Seid - Chapel Hill NC, US

Assignee:

Med Immune, LLC - Gaithersburg MD
The Regents of the University of Colorado - Boulder CO

International Classification:

A61K 9/14

US Classification:

424489, 424450, 4352351, 435170

Abstract:

This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles.