Benoit P Schmitt from 15 Pintail, Irvine, CA 92604, age 61, Phone: 949-421-7977

Stable Galenic Preparations Comprising A Benzimidazol And Method For The Production Thereof
view source
US Patent:

20030114494, Jun 19, 2003
Filed:

Aug 26, 2002
Appl. No.:

10/149068
Inventors:

Benoit Schmitt - Irvine CA, US
International Classification:

A61K031/4439
A61K009/24
A61K009/14
US Classification:

514/338000, 424/471000
Abstract:

The invention relates to a novel benzimidazole formulation and to a process for its production. The benzimidazole formulation comprises a layer comprising the benzimidazole compound together with an acidic reacting compound.

Extended Release Pharmaceutical Tablet Of Metformin
view source
US Patent:

20040161461, Aug 19, 2004
Filed:

Feb 4, 2004
Appl. No.:

10/771987
Inventors:

Pawan Seth - Irvine CA, US
Benoit Schmitt - Irvine CA, US
International Classification:

A61K009/24
US Classification:

424/471000
Abstract:

The invention provides an extended release pharmaceutical tablet containing: (i) a core comprising by weight, based on the core weight, about 70% to about 99% metformin and pharmaceutically acceptable excipients; and (ii) a coating surrounding said core, wherein said coating is permeable to metformin. The extended release tablets of the invention exhibit a dissolution profile such that after about 2 hours, from about 7% to about 60% of the metformin is released; after about 4 hours, from about 15% to about 90% of the metformin is released; after about 8 hours, from about 50% to about 100% of the metformin is released; after about 12 hours, more than about 75% of the metformin is released.

Statin Compositions
view source
US Patent:

20090226515, Sep 10, 2009
Filed:

Mar 4, 2008
Appl. No.:

12/041976
Inventors:

Benoit Schmitt - Irvine CA, US
Laurent Imler - Irvine CA, US
Assignee:

Pharma PASS II LLC - Irvine CA
International Classification:

A61K 9/20
A61K 31/40
A61P 7/00
US Classification:

424465, 514423
Abstract:

The present invention relates to an improved statin or salt thereof composition, especially an atorvastatin composition, which exhibits enhanced dissolution properties in acidic media. It comprises a statin active ingredient and an aminoalkyl methacrylate copolymer dispersed therein, such as dimethyl aminoethyl methacrylate. The invention also relates to a process for preparing the improved composition and to methods of using it for the treatment of dyslipidemia.

Sartan Compositions
view source
US Patent:

20090226516, Sep 10, 2009
Filed:

Mar 4, 2008
Appl. No.:

12/042003
Inventors:

Benoit Schmitt - Irvine CA, US
Laurent Imler - Irvine CA, US
Assignee:

Pharma PASS II LLC - Irvine CA
International Classification:

A61K 9/20
A61K 31/41
A61P 9/12
A61P 9/00
A61P 9/04
US Classification:

424465, 514381
Abstract:

The invention provides a sartan or salt thereof composition having a dissolution in acetate buffer at pH 4.0 using USP type I method basket 10 Mesh at 75 rpm, of at least 20% after 90 minutes, 50% after 160 minutes, and 70% after 240 minutes

Xetine Compositions
view source
US Patent:

20090227682, Sep 10, 2009
Filed:

Mar 4, 2008
Appl. No.:

12/041995
Inventors:

Benoit Schmitt - Irvine CA, US
Laurent Imler - Irvine CA, US
Assignee:

Pharma PASS II LLC - Irvine CA
International Classification:

A61K 31/137
C07C 217/62
A61P 25/24
US Classification:

514651, 564443
Abstract:

The invention provides a xetine or salt thereof composition having a dissolution in a phosphate buffer at pH 6.8, using USP basket 10 Mesh at 75 rpm, of at least 15% at 60 minutes, of at least 40% at 120 minutes, of at least 70% at 300 minutes.

Composition Comprising A Benzimidazole And Process For Its Manufacture
view source
US Patent:

20130251791, Sep 26, 2013
Filed:

May 16, 2013
Appl. No.:

13/895492
Inventors:

Pawan Seth - Irvine CA, US
Benoit Schmitt - Irvine CA, US
International Classification:

A61K 9/50
A61K 31/4439
A61K 9/20
US Classification:

424452, 424490, 424465, 514338, 264115, 427 214
Abstract:

The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being substantially free of binder. The invention also provides a process for manufacturing the composition of the invention.

Composition Comprising A Benzimidazole And Process For Its Manufacture
view source
US Patent:

20150164817, Jun 18, 2015
Filed:

Feb 27, 2015
Appl. No.:

14/633766
Inventors:

Pawan Seth - Irvine CA, US
Benoit Schmitt - Irvine CA, US
International Classification:

A61K 9/50
A61K 31/4439
A61K 9/20
Abstract:

The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being substantially free of binder. The invention also provides a process for manufacturing the composition of the invention.

Pharmaceutical Compositions Comprising Niacin And A Process For Their Preparation
view source
US Patent:

20140220123, Aug 7, 2014
Filed:

Feb 1, 2013
Appl. No.:

13/756588
Inventors:

Benoit Schmitt - Irvine CA, US
Laurent Imler - Irvine CA, US
Assignee:

PHARMA PASS II LLC - Irvine CA
International Classification:

A61K 9/20
A61K 9/28
A61J 3/10
A61K 31/455
US Classification:

424465, 514356, 264115, 427 214
Abstract:

A process for the manufacture of compositions containing niacin, the process including a first compaction step of niacin or a pharmaceutically acceptable salt thereof, then a second compaction step of a dry blend comprising niacin and microcrystalline cellulose and a further compression step into tablets. Stable tablet compositions including niacin are capable of extended release of niacin.

view source

Location:

Irvine, CA

Industry:

Pharmaceuticals

Work:

Leo Pharma
Director of Research
Mepha Jan 1989 - Apr 1995
Analytical R and D

view source

Location:

Orange County, California Area

Industry:

Pharmaceuticals

Benoit P Schmitt