Meilei Jin - Shanghai, CN Yun Peng - Shanghai, CN Hong Zou - Shanghai, CN Guoping Zhao - Shanghai, CN Xuedong Zhou - Shanghai, CN Anne O. Chua - Wayne NJ, US Robert A. Goodnow - Gillette NJ, US Ulrich A. Gubler - Glen Ridge NJ, US Holly Hilton - Kearny NJ, US David Fu-Chi Mark - West Windsor NJ, US Mitchell Lee Martin - Verona NJ, US James Andrew Rosinski - Nutley NJ, US
Assignee:
SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES - Shanghai F.HOFFMANN-LA ROCHE AG - Basal
International Classification:
A61K 38/17 C07K 14/71 C12Q 1/68
US Classification:
514 12, 530350, 435 6
Abstract:
The present invention provides mammalian GPR39 gene, its coded products, and the uses in regulating appetite and pain sensitivity. A pharmaceutical composition and a health product comprising GPR39 protein are also provided. The health product and the pharmaceutical composition for suppressing appetite or decreasing pain sensitivity comprise a safe and efficient amount of antagonists of mammalian GPR39 protein (for example, 0.01-99%) and a bromatologically or pharmaceutically acceptable carrier in a suitable amount (for example 1-99.99 wt %).
Anne On Chua - Wayne NJ Ulrich Andreas Gubler - Glen Ridge NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07K 14715
US Classification:
530350
Abstract:
This invention relates to substantially pure Interleukin-12 receptor cDNAs and protein and uses therefore. The Interleukin-12 receptor is shown to be a member of the cytokine receptor superfamily and has a high homology to human gp130.
Recombinant Dna Encoding Human Receptor For Interleukin-12
Anne O. Chua - Wayne NJ Ulrich A. Gubler - Glen Ridge NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12N 510 C12N 1512
US Classification:
4352523
Abstract:
This invention relates to substantially pure Interleukin-12 receptor cDNAs and protein and uses therefore. The Interleukin-12 receptor is shown to be a member of the cytokine receptor superfamily and has a high homology to human gp130.
Name / Title
Company / Classification
Phones & Addresses
Anne O Chua Director, Secretary, Director, Secretary
MRM ENTERPRISES, INC Home Health Care Services
410 N Dillard St, Winter Garden, FL 34787 2248 Meridian Blvd SUITE H, Minden, NV 89423