Anle Yang from 10615 Corte Acuario, San Diego, CA 92130, age 59, Phone: 858-755-2658

Us Patents

Carbonylamino Pyrrolopyrazoles, Potent Kinase Inhibitors
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US Patent:

7884117, Feb 8, 2011
Filed:

Dec 12, 2006
Appl. No.:

12/158241
Inventors:

Junhun Zhang - San Diego CA, US
Anle Yang - San Diego CA, US
Susan Elizabeth Kephart - San Diego CA, US
Liming Dong - Shanghai, CN
Chuangxing Guo - San Diego CA, US
Yufeng Hong - San Diego CA, US
Mary Catherine Johnson - San Diego CA, US
Indrawan James McAlpine - San Diego CA, US
Jayashree Tikhe - San Diego CA, US
Haitao Li - Rockville MD, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

A61K 31/422
A61K 31/4162
C07D 261/06
C07D 231/54
US Classification:

514378, 514406, 548248, 5483605
Abstract:

Carbonylamino Pyrrolopyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.

Pyrrolopyrazole, Potent Kinase Inhibitors
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US Patent:

8067591, Nov 29, 2011
Filed:

Dec 28, 2005
Appl. No.:

11/813658
Inventors:

Junhu Zhang - San Diego CA, US
Chuangxing Guo - San Diego CA, US
Djamal Bouzida - San Diego CA, US
Liming Dong - San Diego CA, US
Haitao Li - San Diego CA, US
Joseph Timothy Marakovits - Encinitas CA, US
Anle Yang - San Diego CA, US
Yufeng Hong - San Diego CA, US
Assignee:

Agouron Pharmaceuticals, Inc. - San Diego CA
Pfizer Inc. - New York NY
International Classification:

C07D 491/00
A01N 43/90
US Classification:

544278, 5142601
Abstract:

Pyrrole pyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.

Pyrrolopyrazoles, Potent Kinase Inhibitors
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US Patent:

8530652, Sep 10, 2013
Filed:

Oct 6, 2011
Appl. No.:

13/267302
Inventors:

Junhu Zhang - San Diego CA, US
Chuangxing Guo - San Diego CA, US
Djamal Bouzida - San Diego CA, US
Liming Dong - San Diego CA, US
Haitao Li - San Diego CA, US
Joseph Timothy Marakovits - Encinitas CA, US
Anle Yang - San Diego CA, US
Yufeng Hong - San Diego CA, US
Assignee:

Agouron Pharmaceuticals, Inc. - San Diego CA
Pfizer Inc. - New York NY
International Classification:

C07D 491/00
A01N 43/90
US Classification:

544278, 5142601
Abstract:

Pyrrole pyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.

Inhibitors Of The Hiv Integrase Enzyme
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US Patent:

20050277662, Dec 15, 2005
Filed:

Apr 25, 2005
Appl. No.:

11/115003
Inventors:

Klaus Dress - San Diego CA, US
Qiyue Hu - Carlsbad CA, US
Ted Johnson - San Clemente CA, US
Michael Plewe - San Diego CA, US
Steven Tanis - Carlsbad CA, US
Hai Wang - San Diego CA, US
Anle Yang - San Diego CA, US
Chunfeng Yin - San Diego CA, US
Junhu Zhang - San Diego CA, US
International Classification:

A61K031/4745
C07D471/02
US Classification:

514300000, 546113000
Abstract:

The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.

Inhibitors Of The Hiv Integrase Enzyme
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US Patent:

20070232644, Oct 4, 2007
Filed:

Aug 26, 2005
Appl. No.:

11/574869
Inventors:

Klaus Dress - San Diego CA, US
Jon Kuehler - San Diego CA, US
Michael Plewe - San Diego CA, US
Anle Yang - San Diego CA, US
Junhu Zhang - San Diego CA, US
International Classification:

A61K 31/44
C07D 471/02
US Classification:

514300000, 546113000
Abstract:

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions comprising compounds of formula (I), and their methods of use in treating HIV-infected mammals.

Resumes

Senior Scientist

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Location:

San Diego, CA

Industry:

Pharmaceuticals

Work:

Pfizer Inc. since Nov 2001
Senior Scientist
DuPont Pharmaceuticals Jan 2000 - Nov 2001
Staff Scientist

Education:

Wuhan University 1983 - 1987
Wuhan University 1983 - 1987
BS, Chemistry Vanderbilt University

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