Ankur Singh

US Patent:

20100272805, Oct 28, 2010

Filed:

Apr 21, 2010

Appl. No.:

12/764456

Inventors:

Ankur Singh - Smyrna GA, US
Krishendu Roy - Austin TX, US
Sudhir Kasturi - Atlanta GA, US

International Classification:

A61K 39/29
A61K 38/20
A61K 9/00
A61K 39/00
A61P 31/20

US Classification:

424484, 424 852, 4242271, 4241841

Abstract:

One embodiment of the current disclosure relates to an immune-modulating composition comprising a hydrogel-forming polymer, an immune-modulating biomolecule operable to recruit or retain an immune cell, and an antigen-related biomolecule. Another embodiment of the current disclosure relates to a method of providing an antigen to an antigen presenting cell in an animal by administering to the animal at an administration site an immune-modulating composition as described above. Next, one forms a hydrogel in-situ from the hydrogel-forming polymer, then recruits at least one antigen presenting cell to the administration site using the immune-modulating biomolecule, and finally inducing phagocytosis of the at least one antigen-related biomolecule by the antigen presenting cell.

US Patent:

20100010102, Jan 14, 2010

Filed:

Jul 9, 2009

Appl. No.:

12/500230

Inventors:

Krishnendu Roy - Austin TX, US
Prinda Wanakule - Austin TX, US
Ankur Singh - Austin TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61K 47/42

US Classification:

5147721, 514773, 514774

Abstract:

The present invention includes compositions and methods for the controlled delivery of active agents, e.g., drugs, based on one or more release triggers found in the environment in which the active agent-loaded particle is located. The composition and methods include a polymer network having a polymer cross-linked by peptides that include one or more proteolytic cleavage sites.

US Patent:

20180298345, Oct 18, 2018

Filed:

Jun 23, 2016

Appl. No.:

15/737973

Inventors:

- Atlanta GA, US
Efrain Cermeno - Atlanta GA, US
Todd Christopher McDevitt - San Francisco CA, US
Ankur Singh - Ithaca NY, US
Susan Napier Thomas - Atlanta GA, US

Assignee:

Georgia Institute of Technology - Atlanta GA

International Classification:

C12N 5/095
C12N 5/071
G01N 33/574

Abstract:

The present invention provides methods of isolating a cancer-associated cell, such as a cancer stem cell or tumor initiating cell or a cell derived therefrom, from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.

US Patent:

20140357506, Dec 4, 2014

Filed:

Jun 21, 2012

Appl. No.:

14/128547

Inventors:

Ankur Singh - Smyrna GA, US
Shalu Suri - Smyrna GA, US
Todd Christopher McDevitt - Atlanta GA, US
Hang Lu - Atlanta GA, US
Andres Jose Garcia - Atlanta GA, US

Assignee:

Georgia Tech Research Licensing, Mail Code: 0415 - Atlanta GA

International Classification:

C12N 5/074
C12Q 1/68
C12N 5/0797
G01N 33/569

US Classification:

506 9, 435379, 435 29, 435 721, 435 612

Abstract:

The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.