Andrew P Goodwin

US Patent:

20030153001, Aug 14, 2003

Filed:

Oct 26, 2001

Appl. No.:

10/055837

Inventors:

David Soane - Piedmont CA, US
Stephen Barry - Oakland CA, US
Andrew Goodwin - Oakland CA, US
David Offord - Castro Valley CA, US
Michael Perrott - San Francisco CA, US

Assignee:

Alnis, LLC

International Classification:

G01N033/53
G01N033/543
C08F002/00
C08F008/00

US Classification:

435/007100, 436/518000, 525/054200, 525/056000, 525/107000

Abstract:

Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites of targets such as nanostructures or macromolecular targets, and may be capable of specifically interacting with such targets. The positions of the functional groups in one embodiment are stabilized by a polymer network. The SPCs are formed by contacting the target with a set of monomers which self-assemble on the target, and then are polymerized into a network to form the synthetic polymer complement. At least a portion of the surface of the resulting SPC thus may include an imprint of the target. The complex of the SPC and the target may be the desired product. Alternatively, the target is released, for example, by controllably expanding and contracting the crosslinked network. The SPC is isolated and used in many applications.

US Patent:

20040126900, Jul 1, 2004

Filed:

May 5, 2003

Appl. No.:

10/257455

Inventors:

Stephen Barry - Oakland CA, US
Andrew Goodwin - Berkeley CA, US
Dominic Casenas - Fremont CA, US
Kevin Lindquist - Albany CA, US
Rachel Decor - Berkeley CA, US

International Classification:

C07K007/08
C07K007/06
G01N033/543

US Classification:

436/523000, 530/330000, 530/329000

Abstract:

The present invention is directed to polymeric nanoparticles functionalized with two or more peptide moieties that possess high affinity to biomolecular targets, the peptide moieties being covalently linked to the nanoparticle polymeric core structure, either directly or via a linker molecule. The invention is further directed to methods of synthesizing these polymeric nanoparticles and to the various applications for which they may be used.

US Patent:

20050129769, Jun 16, 2005

Filed:

Nov 22, 2004

Appl. No.:

10/995880

Inventors:

Stephen Barry - Alamo CA, US
Andrew Goodwin - San Leandro CA, US
Rachel Decor - Berkeley CA, US

International Classification:

C08G063/48
C08G063/91
A61K009/14
C08B033/02
C07C323/25

US Classification:

424486000, 525054200, 536110000, 562557000

Abstract:

Hydrophilic polymeric nanoarticles comprising a polymeric scaffold and one or more therapeutic agents, such as drug or drug-conjugate molecules, covalently attached to the scaffold. The articles may further optionally comprise recognition elements (REs) that bind to biomolecular structures expressed on certain cells or in certain tissues, to facilitate targeting and/or delivery.

US Patent:

20110208301, Aug 25, 2011

Filed:

Feb 23, 2011

Appl. No.:

13/033474

Inventors:

David Anvar - Sunnyvale CA, US
Andrew Goodwin - San Leandro CA, US
David Chazan - Palo Alto CA, US

International Classification:

A61F 2/16
G02C 7/04
C08K 5/5415

US Classification:

623 613, 523107, 106481

Abstract:

Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.

US Patent:

20210290371, Sep 23, 2021

Filed:

Mar 12, 2021

Appl. No.:

17/200047

Inventors:

- Fribourg, CH
Andrew GOODWIN - San Leandro CA, US
David CHAZAN - Palo Alto CA, US

Assignee:

Alcon Inc. - Fribourg

International Classification:

A61F 2/16
C07F 7/18
C07F 7/20
C08G 77/34
A61L 27/14
A61L 27/50

Abstract:

Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.

US Patent:

20150087743, Mar 26, 2015

Filed:

Nov 26, 2014

Appl. No.:

14/555001

Inventors:

David J. ANVAR - Sunnyvale CA, US
Andrew GOODWIN - San Leandro CA, US
David CHAZAN - Palo Alto CA, US

International Classification:

A61F 2/16
A61L 27/50
A61L 27/14

US Classification:

523106, 10628714

Abstract:

Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.