In a preferred embodiment, a lure-segregating compartmentalized fishing tackle box having forward and rearward compartments, with the forward compartment space divided into a plurality of forwardly and rearwardly rows of separate lure-holding segregated spaces segregated into rows of laterally serially-arranged separate spaces by a removable insert forming upright walls to the separate spaces. Forward row walls are shorter than rearward row walls and opposite ends of the tackle box have side wall portions of varying heights corresponding to the shorter forward row walls and to the higher rearward row walls. The forward compartment and the rearward compartment are separated by an upright wall partition positioned for equalizing forward and rearward mass substantially equally of the tackle box and for joining to an upper portion thereof a handle structure having lid-fastening apertures therein receivable of a back compartment lid on the back upright wall of the tackle box. Separate forward hinged lids are securable over the lure-holding spaces, and an accessory drawer is provided beneath the first and second compartments and slidably inserted through a forward upright wall of the tackle box. The rearward wall of the tackle box slants rearwardly from bottom to top whereby an upper space of the rearward compartment is wider in a forward to rearward direction than the lower space of that compartment.