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Alberto F Lopapa

age ~86

from Van Nuys, CA

Also known as:
  • Alberto Dr Lopapa
  • Alberto F Opapa
  • Alberto E Lopapa
  • Alberto I Lopapa

Alberto Lopapa Phones & Addresses

  • Van Nuys, CA
  • Glendale, CA
  • Los Angeles, CA
  • Woodland Hills, CA
  • North Hollywood, CA

Us Patents

  • Methods For The Detection And Quantitation Of Immunological Substances

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  • US Patent:
    46210636, Nov 4, 1986
  • Filed:
    Oct 12, 1982
  • Appl. No.:
    6/433732
  • Inventors:
    Philip J. Wyatt - Santa Barbara CA
    Alberto F. Lopapa - Los Angeles CA
  • Assignee:
    The Center for Immunological Studies - Los Angeles CA
  • International Classification:
    G01N 33543
  • US Classification:
    436501
  • Abstract:
    The invention provides improved methods and unique instrumentation for the detection and for the quantitation of chemical substances and has particular application for the detection and for the quantitation of immunological substances. In one embodied form, the inventive method comprises the steps of (a) affixing to a surface a reactant material known to interact and to bind to, or to have a relatively high affinity for, the immunological substance to be detected, the substance being present in at least one medium; (b) impinging the affixed surface with a source of coherent radiation; (c) measuring a pattern of radiation scattered from the affixed surface; (d) reacting the affixed surface with at least one medium containing the immunological substance; (e) impinging the reacted affixed surface with substantially the same coherent radiation at substantially the same aspect and orientation utilized to perform step (b); (f) measuring a pattern of radiation scattered from the reacted affixed surface; and (g) comparing the patterns of radiation derived from steps (b) and (f) to determine any differentiations therebetween. The unique instrumentation provides a complete system for convenient, precise quantitative measurement of immunological substances sought to be detected. The inventive methods and instrumentation thereby provide an extremely sensitive, yet relatively rapid, means for quantitative and qualitative analyses which has application to a broad range of biological fields.
  • In-Vitro Diagnostic Method For Detection Of Acetylsalicylic Acid Ingestion

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  • US Patent:
    43930409, Jul 12, 1983
  • Filed:
    Mar 24, 1981
  • Appl. No.:
    6/246993
  • Inventors:
    Alberto F. Lopapa - Los Angeles CA
    Theodore D. Hall - Los Angeles CA
  • Assignee:
    Lopapa Institute, Inc. - Los Angeles CA
  • International Classification:
    G01N 3356
    G01N 3358
    G01N 3360
  • US Classification:
    424 1
  • Abstract:
    An in-vitro diagnostic method is provided for detecting acetylsalicylic acid ingestion by a patient by utilizing radioimmunoassay procedure. The method comprises the steps of: derivatizing acetylsalicylic acid with a protein moiety being effected in a molar ratio of about one mole of protein to at least thirty moles of acetylsalicylic acid; coupling the acetylsalicylic acid derivatized protein with a water insoluble solid matrix by binding with a selected chemical agent; obtaining a sample of patient serum; freeze drying the serum including any antibodies specific to acetylsalicylic acid to concentrate the serum to a solid phase; diluting the freeze dried serum to from about 100 to about 1,000 times its original concentration; incubating the solid matrix coupled with the acetylsalicylic acid derivatized protein with the concentrated serum for a sufficient period of time to allow any antibodies specific to acetylsalicylic acid to attach to the solid matrix coupled with the acetylsalicylic acid derivatized protein, the incubation occurring for at least 24 hours at a temperature range of from about 4. degree. C. to about 42. degree. C. ; thereafter, incubating the solid phase bound with specific antibodies present with radioactively labelled antibodies specific to acetylsalicylic acid derivatized protein obtained from a test animal for a sufficient period of time to allow binding between the labelled antibodies and the matrix; separating the mixture into distinct liquid and solid phases; and measuring the radiation emitted from at least one of the separated phases.
Name / Title
Company / Classification
Phones & Addresses
Alberto Lopapa
President
Lopapa Immunology Center, Inc
3580 Wilshire Blvd, Los Angeles, CA 90010

Youtube

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Alberto Francisco Lopapa June 20, 1937 - December 21, 2010

  • Category:
    People & Blogs
  • Uploaded:
    27 Dec, 2010
  • Duration:
    8m 23s

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