Albert Ming Tam

US Patent:

6379891, Apr 30, 2002

Filed:

Apr 19, 2000

Appl. No.:

09/553427

Inventors:

Gregory R. Reyes - Palo Alto CA
Patrice O. Yarbough - Redwood Shores CA
Daniel W. Bradley - Lawrenceville GA
Krzysztof Z. Krawczynski - Tucker GA
Albert Tam - San Francisco CA
Kirk E. Fry - Palo Alto CA

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC
Genelabs Technologies, Inc., - Redwood City

International Classification:

C12Q 168

US Classification:

435 6, 536 221

Abstract:

Viral proteins derived from an enterically transmitted non-A/non-B viral hepatitis agent (HEV) are disclosed. In one embodiment, the protein is immunologically reactive with antibodies present in individuals infected with the viral hepatitis agent. This protein is useful in a diagnostic method for detecting infection by the enterically transmitted agent. Specific epitopes have been identified that are reactive with sera of individual infected with different strains of HEV. Also disclosed are DNA probes derived from a cloned sequence of the viral agent. These probes are useful for identifying and sequencing the entire viral agent and for assaying the presence of the viral agent in an infected sample, by using probe-specific amplification of virus-derived DNA fragments.

US Patent:

6455492, Sep 24, 2002

Filed:

Apr 20, 1992

Appl. No.:

07/870985

Inventors:

Gregory R. Reyes - Palo Alto CA
Daniel W. Bradley - Lawrenceville GA
Michael A. Purdy - Atlanta GA
Albert W. Tam - San Francisco CA
Krzysztof Z. Krawczynski - Tucker GA
Patrice O. Yarbough - Union City CA

Assignee:

Genelabs Technologies, Inc. - Redwood City CA

International Classification:

A01N 3718

US Classification:

514 2, 435 5, 4352351, 5303871, 5303883, 53038835

Abstract:

Antigen and antibody vaccine composition effective in preventing hepatitis E virus (HEV) infection are disclosed. The antigen composition includes peptides corresponding to carboxyl terminal end regions of the second and third open reasing frames of the HEV genome. The composition is effective in preventing HEV infection after vaccination. The antibody composition contains an antibody effective to block HEV infection of human primary hepatocytes in culture.

US Patent:

6753878, Jun 22, 2004

Filed:

Mar 8, 1999

Appl. No.:

09/264347

Inventors:

Alan Heirich - Half Moon Bay CA
Laurent Moll - Palo Alto CA
Mark Shand - Palo Alto CA
Albert Tam - Fremont CA
Robert W. Horst - Saratoga CA

Assignee:

Hewlett-Packard Development Company, L.P. - Houston TX

International Classification:

G06F 1516

US Classification:

345629, 345619, 345630, 345632, 345634

Abstract:

An image generator is organized into a plurality of rendering engines, each of which renders an image of a part scene and provides the part image to a merge engine associated with that rendering engine. The image is a part image in that it usually contains less than all of the objects in the image to be rendered. The merge engine merges the part image from its associated rendering engine with the part image provided by a prior merge engine and provides the merged part image to a next merge engine. One or more merge engines are designated the output merge engines and these output merge engines output a merged part image that is (a portion of) the ultimate output of the image generator, the full rendered image. Each merge engine performs its merge process on the pixels it has from its rendering engine and from its prior neighbor merge engine, in a pipelined manner and without necessarily waiting for all of the pixels of the part image or the merged part image.

US Patent:

6838556, Jan 4, 2005

Filed:

Jun 6, 2001

Appl. No.:

09/875453

Inventors:

Jungsuh P. Kim - Palo Alto CA, US
Douglas B. Starr - Mountain View CA, US
Albert W. Tam - San Francisco CA, US
Megan E. Laurance - San Francisco CA, US
Emil F. Michelotti - Foster City CA, US
Mark D. Velligan - Montara CA, US
Derek R. Latour - Hayward CA, US
Rita L. Thomas - San Jose CA, US
Ana Kongpachith - Union City CA, US
Liana T. Sheppard - Redwood City CA, US
Moon Young Kim - Redwood City CA, US
Thomas W. Bruice - Carlsbad CA, US

Assignee:

Genelabs Technologies, Inc. - Redwood City CA

International Classification:

C12N 1511

US Classification:

536 241

Abstract:

This invention provides nucleic acid sequences, vectors and host cells comprising regulatory regions associated with various promoters including a cyclin D1 promoter, a CD40L promoter, three HBV promoters (core, pre-S1 and HBV-X), a vancomycin-resistant enterococci (VRE) promoter, an androgen receptor promoter, a Her2 promoter, and β-lactamase promoter. The invention further provides methods of regulating gene expression comprising the regulatory regions of such promoters.

US Patent:

7094406, Aug 22, 2006

Filed:

May 7, 2001

Appl. No.:

09/851410

Inventors:

Gregory R. Reyes - Palo Alto CA, US
Patrice O. Yarbough - Union City CA, US
Daniel W. Bradley - Lawrenceville GA, US
Krzysztof Z. Krawczynski - Norcross GA, US
Albert W. Tam - San Francisco CA, US
Kirk E. Fry - Palo Alto CA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services and Genelabs Technologies, Inc. - Washington DC

International Classification:

A61K 39/29
C07K 4/02
C07K 7/00
C07K 14/08

US Classification:

4241891, 4242281, 530300, 530350, 530324, 530325, 530326, 530327, 530328, 4352351

Abstract:

Viral proteins derived from an enterically transmitted non-A/non-B viral hepatitis agent (HEV) are disclosed. In one embodiment, the protein is immunologically reactive with antibodies present in individuals infected with the viral hepatitis agent. This protein is useful in a diagnostic method for detecting infection by the enterically transmitted agent. Specific epitopes have been identified that are reactive with sera of individual infected with different strains of HEV. Also disclosed are DNA probes derived from a cloned sequence of the viral agent. These probes are useful for identifying and sequencing the entire viral agent and for assaying the presence of the viral agent in an infected sample, by using probe-specific amplification of virus-derived DNA fragments.

US Patent:

7189506, Mar 13, 2007

Filed:

Mar 3, 2000

Appl. No.:

09/518297

Inventors:

Moon Young Lim - Redwood City CA, US
Cynthia A. Edwards - Morgan Hill CA, US
Kirk E. Fry - Palo Alto CA, US
Thomas W. Bruice - Carlsbad CA, US
Douglas B. Starr - Mountain View CA, US
Megan E. Laurance - San Francisco CA, US
Yan Kwok - Sunnyvale CA, US
Albert W. Tam - San Francisco CA, US

Assignee:

Genelabs Technologies, Inc. - Redwood City CA

International Classification:

C12Q 1/68
C07H 21/04

US Classification:

435 6, 435 721, 435 723, 435 691, 4352351, 436501, 536 231, 536 234, 536 235, 536 236, 536 237

Abstract:

The present invention provides molecular switch system methods and compositions for use in regulatable gene expression. The system includes a nucleic acid construct which has a DNA response sequence for a transcriptional regulatory protein operably linked to a promoter, a compound binding sequence in the vicinity of the DNA response sequence, a transgene under the control of the promoter; and a DNA binding compound. In some cases, the molecular switch system further includes a nucleic acid sequence encoding a transcriptional regulatory protein operably linked to a second promoter. The invention further provides a method for screening compounds for the ability to function in the molecular switch system and thereby regulate gene expression.

US Patent:

20020174417, Nov 21, 2002

Filed:

Mar 30, 2001

Appl. No.:

09/823001

Inventors:

Michael Sijacic - Sunnyvale CA, US
Edwin Khodabakchian - Sunnyvale CA, US
Albert Tam - Sunnyvale CA, US
Michal Chmielewski - San Jose CA, US

International Classification:

G06F009/45

US Classification:

717/147000

Abstract:

A method of creating and defining a custom data field within a process management system includes creating a file to specify visible field properties of the custom data field and defining a model of the custom data field. The file and the model may be packaged into an archive file. The custom data field may be inserted and the archive file is added into the process management system as a new class. The process management system may be deployed with the new class and the process management system may be tested with the new class.

US Patent:

20030093500, May 15, 2003

Filed:

Oct 9, 2002

Appl. No.:

10/268856

Inventors:

Edwin Khodabakchian - Palo Alto CA, US
Albert Tam - Palo Alto CA, US
Weigun Mi - Santa Clara CA, US
Muruganantham Chinnananchi - Mountain View CA, US
Roman Dobrik - San Jose CA, US

International Classification:

G06F015/16

US Classification:

709/219000

Abstract:

A system and method for managing service interactions launches a process that is defined by a programming abstraction based on a syntax of a general purpose programming language. Interaction with a service, such as a web-based service, is initiated and the process requests the service to perform an action. Execution of the process is suspended until a response is received from the service. Execution of the process continues after receiving a response from the service.