Alain Noncovich from 4767 Nexus Center Dr, San Diego, CA 92121, age 50

Us Patents

Compounds Useful As Modulators Of Trpm8
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US Patent:

20130324557, Dec 5, 2013
Filed:

Nov 4, 2011
Appl. No.:

13/883349
Inventors:

Chad Priest - Encinitas CA, US
Alain Noncovich - San Diego CA, US
Andrew Patron - San Marcos CA, US
Jane Ung - San Diego CA, US
Assignee:

SENOMYX, INC. - San Diego CA
International Classification:

C07D 409/12
A01N 43/56
C07D 333/20
A01N 43/10
C07D 413/12
A01N 43/76
A01N 43/80
A01N 43/40
C07D 231/40
C07D 409/14
C07D 277/28
A01N 43/60
C07D 471/04
A01N 43/90
A23L 1/22
A61K 8/49
US Classification:

51425505, 5483657, 514407, 549 77, 514438, 548234, 514377, 548246, 514380, 5462814, 514336, 5483725, 514338, 548204, 514365, 544405, 546121, 514300, 435375, 426535, 426536, 426537, 426538
Abstract:

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formula (I) and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

Compositions And Methods For The Treatment Of Viral Infections
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US Patent:

20220257787, Aug 18, 2022
Filed:

Apr 21, 2021
Appl. No.:

17/236722
Inventors:

- San Diego CA, US
Daniel C. BENSEN - Carlsbad CA, US
Allen BORCHARDT - San Diego CA, US
Thomas P. BRADY - San Diego CA, US
Zhi-Yong CHEN - La Jolla CA, US
Jason COLE - San Diego CA, US
Simon DOEHRMANN - San Diego CA, US
Wanlong JIANG - San Diego CA, US
Thanh LAM - San Diego CA, US
Alain NONCOVICH - La Jolla CA, US
Leslie W. TARI - Solana Beach CA, US
International Classification:

A61K 47/68
Abstract:

Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).

Compositions And Methods For The Treatment Of Respiratory Syncytial Virus
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US Patent:

20230082611, Mar 16, 2023
Filed:

Jun 12, 2020
Appl. No.:

17/618347
Inventors:

- San Diego CA, US
Thomas P. BRADY - San Diego CA, US
Zhi-Yong CHEN - La Jolla CA, US
Travis James HAUSSENER - San Diego CA, US
Alain NONCOVICH - La Jolla CA, US
Leslie W. TARI - Solana Beach CA, US
International Classification:

A61K 47/68
A61K 45/06
A61K 47/54
Abstract:

Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral RSV F protein (e.g., Presatovir, MDT 637, JNJ 179, or an analog thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., RSV infections).

Compositions And Methods For The Treatment Of Viral Infections
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US Patent:

20210220478, Jul 22, 2021
Filed:

Mar 5, 2021
Appl. No.:

17/194093
Inventors:

- San Diego CA, US
Daniel C. BENSEN - Carlsbad CA, US
Allen BORCHARDT - San Diego CA, US
Thomas P. BRADY - San Diego CA, US
Zhi-Yong CHEN - La Jolla CA, US
Jason COLE - San Diego CA, US
Simon DOEHRMANN - San Diego CA, US
Wanlong JIANG - San Diego CA, US
Thanh LAM - San Diego CA, US
Alain NONCOVICH - La Jolla CA, US
Leslie W. TARI - Solana Beach CA, US
Assignee:

Cidara Therapeutics, Inc. - San Diego CA
International Classification:

A61K 47/68
A61P 31/16
Abstract:

Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).

Compounds Useful As Modulators Of Trpm8
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US Patent:

20200010425, Jan 9, 2020
Filed:

Sep 18, 2019
Appl. No.:

16/574657
Inventors:

- Plainsboro NJ, US
Andrew Patron - San Marcos CA, US
Chad Priest - Cardiff CA, US
Donald Karanewsky - Escondido CA, US
Rachel Kimmich - San Diego CA, US
Brant Clayton Boren - San Diego CA, US
Jeffrey Robert Hammaker - San Diego CA, US
Volodymyr Chumakov - San Diego CA, US
Wen Zhao - San Diego CA, US
Alain Noncovich - San Diego CA, US
Jane Ung - San Diego CA, US
International Classification:

C07D 231/20
A23L 33/10
C07D 333/22
C07D 233/78
C07D 235/02
C07D 401/06
C07D 403/06
C07D 239/22
C07D 405/06
C07D 409/06
C07D 207/32
C07D 213/50
A23L 2/52
C07C 233/31
C07D 207/26
C07D 207/333
C07D 239/62
Abstract:

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

Compounds Useful As Modulators Of Trpm8
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US Patent:

20190177308, Jun 13, 2019
Filed:

Sep 21, 2016
Appl. No.:

15/764204
Inventors:

- San Diego CA, US
Alain Noncovich - San Diego CA, US
Timothy Davis - San Diego CA, US
Chad Priest - San Diego CA, US
Joseph R. Fotsing - San Diego CA, US
Jane Ung - San Diego CA, US
Catherine Tachdjian - San Diego CA, US
International Classification:

C07D 409/12
A23L 33/10
A23L 2/52
B65D 81/18
B65D 65/38
Abstract:

The present disclosure relates to compounds which are useful as cooling sensation compounds.

Compounds Useful As Modulators Of Trpm8
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US Patent:

20180289704, Oct 11, 2018
Filed:

May 31, 2018
Appl. No.:

15/994235
Inventors:

- San Diego CA, US
Alain Noncovich - San Diego CA, US
Andrew Patron - San Marcos CA, US
Jane Ung - San Diego CA, US
International Classification:

A61K 31/497
C07C 233/11
A61K 31/165
A61K 31/381
A61K 31/415
A61K 31/4155
A61K 31/422
A61K 31/426
A61K 31/437
A61K 31/4409
A61K 31/4436
A23L 33/10
A01N 37/18
A01N 43/78
A23L 27/00
C07D 409/12
A01N 43/90
A01N 43/56
A01N 43/60
A01N 43/76
A01N 43/80
A61K 8/49
A01N 43/10
A01N 43/40
Abstract:

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formula (I) and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

Compounds Useful As Modulators Of Trpm8
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US Patent:

20170369447, Dec 28, 2017
Filed:

Sep 6, 2017
Appl. No.:

15/697301
Inventors:

- San Diego CA, US
Andrew Patron - San Marcos CA, US
Chad Priest - Cardiff CA, US
Donald Karanewsky - Escondido CA, US
Rachel Kimmich - San Diego CA, US
Brant Clayton Boren - San Diego CA, US
Jeffrey Robert Hammaker - San Diego CA, US
Volodymyr Chumakov - San Diego CA, US
Wen Zhao - San Diego CA, US
Alain Noncovich - San Diego CA, US
Jane Ung - San Diego CA, US
International Classification:

C07D 231/20
A23L 33/10
C07D 403/06
C07D 401/06
C07D 333/22
C07D 239/62
C07D 239/22
C07D 235/02
C07D 233/78
C07D 213/50
C07D 207/333
C07D 207/32
C07D 207/26
C07C 233/31
C07D 405/06
A23L 2/52
C07D 409/06
C07C 2601/04
C07C 2601/16
Abstract:

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

Resumes

Senior Scientist Ii

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Location:

8621 Via Mallorca, La Jolla, CA 92037

Industry:

Biotechnology

Work:

Senomyx, Inc. since Jan 2009
Senior Scientist
Senomyx Inc. Oct 2006 - Dec 2008
Scientist
The Scripps Reasearch Institute Mar 2005 - Jun 2006
Research Associate

Education:

Universita' del Piemonte Orientale "A. Avogadro" 2001 - 2004
Doctorate, Organic Chemistry Università degli Studi di Torino 2002 - 2002
Licensed Chemist, Chemistry Università degli Studi di Torino 1994 - 2001
Laurea in Chimica (Ms equivalent), Chemistry ITIS "Q. Sella" 1989 - 1994
Diploma di Perito Chimico Industriale, Industrial Chemistry

Skills:

Organic Chemistry
Medicinal Chemistry
Organic Synthesis
Drug Discovery
Purification
Drug Design
Biotechnology
Chemistry
Lc Ms
Life Sciences
Hplc
Drug Development
Lead Change
Gpcrs
High Throughput Screening
Total Synthesis
Biochemistry
Liquid Chromatography Mass Spectrometry
Parallel Synthesis
Ion Channels
High Performance Liquid Chromatography
Bioconjugate Chemistry
Adcs

Languages:

English
Italian

Certifications:

Licensed Chemist -