Romyr Dominique - Wayne NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Qi Qiao - Bloomfield NJ, US Achyutharao Sidduri - Livingston NJ, US Jefferson Wright Tilley - North Caldwell NJ, US
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
A61K 31/497 C07D 241/04
US Classification:
51425212, 544358
Abstract:
Provided herein are compounds of the formula (I):.
Romyr Dominique - Wayne NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Qi Qiao - Bloomfield NJ, US Achyutharao Sidduri - Livingston NJ, US Jefferson Wright Tilley - North Caldwell NJ, US
Assignee:
Hoffman-La Roche Inc. - Nutley NJ
International Classification:
C07D 317/44 A61K 31/405
US Classification:
549447, 514415
Abstract:
Provided herein are compounds of the formula (I):.
Romyr Dominique - Wayne NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Jianping Lou - Hillsborough NJ, US Qi Qiao - Bloomfield NJ, US Achyutharao Sidduri - Livingston NJ, US Jefferson Wright Tilley - North Caldwell NJ, US
Romyr Dominique - Wayne NJ, US Nader Fotouhi - Basking Ridge NJ, US Paul Gillespie - Westfield NJ, US Robert Alan Goodnow - Gillette NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Qi Qiao - Bloomfield NJ, US Achyutharao Sidduri - Livingston NJ, US
Paul Gillespie - Westfield NJ, US Robert Goodnow - Gillette NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Qiang Zhang - Parsippany NJ, US
International Classification:
A61K 31/538 A61K 31/4709 A61K 31/453 A61K 31/445
US Classification:
514230500, 514314000, 514319000, 514320000
Abstract:
Provided herein are compounds of the formula (1): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Pyrazolones As Inhibitors Of 11B-Hydroxysteroid Dehydrogenase
Bruce Banner - Wayne NJ, US Joseph Bilotta - Astoria NY, US Nader Fotouhi - Basking Ridge NJ, US Paul Gillespie - Westfield NJ, US Robert Goodnow - Gillette NJ, US Matthew Hamilton - Hackettstown NJ, US Nancy-Ellen Haynes - Cranford NJ, US Agnieszka Kowalczyk - Mine Hill NJ, US Alexander Mayweg - Loerrach, DE Michael Myers - Ramsey NJ, US Nathan Scott - Livingston NJ, US Kshitij Thakkar - Clifton NJ, US Jefferson Tilley - North Caldwell NJ, US
International Classification:
A61K 31/416 C07D 231/54
US Classification:
514405000, 548359100
Abstract:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Integrin Antagonist Conjugates For Targeted Delivery To Cells Expressing Lfa-1
The invention relates to compounds of formula I:wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to LFA-1 integrin antagonists to target cells expressing LFA-1.
Roche Mar 2002 - Dec 2012
Associate Principal Scientist
Novartis 2001 - 2002
Chemist
Education:
Mercer Institute of Management and Technology Trainings 2013
Vanderbilt University 2000
Vanderbilt University 1994 - 2000
Doctorates, Doctor of Philosophy, Chemistry
Vanderbilt University 1997
Master of Science, Masters
Nicolaus Copernicus University 1989 - 1994
Master of Science, Masters, Organic Chemistry
Skills:
Drug Discovery Drug Design Drug Development Technology Transfer Technical Writing Medicinal Chemistry Synthetic Organic Chemistry Parallel Synthesis Sirna Delivery Heterocyclic Chemistry Maldi Tof Lc Ms Dna Chemistry Chromatography Pharmaceutical Industry Biotechnology Bioconjugate Chemistry Combinatorial Chemistry Hplc Nmr Assay Development Sirna Organic Chemistry High Throughput Screening Dna Mass Spectrometry Organic Synthesis Biochemistry Small Molecules
Moim hobby jest sztuka pod każdym względem. Oprócz wyrobu biżuterii zajmuję się muzyką (uczę się gry na skrzypcach, pianinie, organach) wykonuję prace artystyczne oraz, od czasu do czasu, fotografuję....