Paul R Moore

US Patent:

20130315915, Nov 28, 2013

Filed:

Apr 30, 2013

Appl. No.:

13/873373

Inventors:

Tao HE - Acton MA, US
Candy LEE - Bethesda MD, US
Karen VAN ORDEN - Gaithersburg MD, US
Paul MOORE - North Bethesda MD, US

Assignee:

Celera Corporation - Alameda CA

International Classification:

G01N 33/574
C07K 14/705
C12Q 1/68
C07K 16/30
C07K 16/40
C12N 9/64
C12N 15/113

US Classification:

4241391, 435219, 530350, 435197, 530395, 424 9464, 424 946, 514 209, 514 212, 536 235, 536 232, 536 245, 5303879, 5303873, 435331, 435375, 435 723, 435 611, 436501, 4352351, 43525233, 43525235, 4352523, 4352542, 435419

Abstract:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

US Patent:

20200291129, Sep 17, 2020

Filed:

Jan 21, 2020

Appl. No.:

16/747791

Inventors:

- San Juan Capistrano CA, US
Tao HE - Acton MA, US
Candy LEE - Bethesda MD, US
Karen VAN ORDEN - Gaithersburg MD, US
Paul MOORE - North Bethesda MD, US

International Classification:

C07K 16/30
C07K 14/705
C07K 16/40
C12N 9/64
C12N 15/113
C12Q 1/6886
G01N 33/574
C07K 14/47
C07K 16/18
C07K 16/28
C12N 9/18

Abstract:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

US Patent:

20180265591, Sep 20, 2018

Filed:

Jan 10, 2018

Appl. No.:

15/866759

Inventors:

- San Clemente CA, US
Tao HE - Acton MA, US
Candy LEE - Bethesda MD, US
Karen VAN ORDEN - Gaithersburg MD, US
Paul MOORE - North Bethesda MD, US

International Classification:

C07K 16/30
C12Q 1/6886
C07K 16/18
C12N 15/113
C07K 14/705
C07K 16/28

Abstract:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

US Patent:

20150361181, Dec 17, 2015

Filed:

Apr 24, 2015

Appl. No.:

14/695680

Inventors:

- Alameda CA, US
Tao HE - Acton MA, US
Candy LEE - Bethesda MD, US
Karen VAN ORDEN - Gaithersburg MD, US
Paul MOORE - North Bethesda MD, US

International Classification:

C07K 16/30
C12N 15/113
C12N 9/64
C12Q 1/68
C07K 16/18
C07K 16/28
C12N 9/18
G01N 33/574
C07K 14/47
C07K 16/40

Abstract:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.