Lisa M Havran from 616 E 6Th St, Florence, NJ 08518, age 54, Phone: 609-499-4458

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia
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US Patent:

6451827, Sep 17, 2002
Filed:

Jan 26, 2001
Appl. No.:

09/771469
Inventors:

John A. Butera - Clarskburg NJ
Craig E. Caufield - New York NY
Russell F. Graceffa - Hampton NH
Alexander Greenfield - Princeton Junction NJ
Eric G. Gundersen - Plainsboro NJ
Lisa Marie Havran - Bordentown NJ
Alan H. Katz - Lawrenceville NJ
Joseph R. Lennox - Morrixville NC
Scott C. Mayer - Robbinsville NJ
Robert E. McDevitt - Somerset NJ
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 3144
US Classification:

514357, 546300, 544162, 548217, 5483355, 548469, 549491, 5142378, 514375, 514399, 514415, 514471
Abstract:

This invention provides compounds of Formula I having the structure wherein: B, C, D, and R are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia
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US Patent:

6765021, Jul 20, 2004
Filed:

Aug 9, 2002
Appl. No.:

10/215438
Inventors:

John A. Butera - Clarkburg NJ
Craig E. Caufield - New York NY
Russell F. Graceffa - Hampton NH
Alexander Greenfield - Princeton Junction NJ
Eric G. Gundersen - Plainsboro NJ
Lisa Marie Havran - Bordentown NJ
Alan H. Katz - Lawrenceville NJ
Joseph R. Lennox - Morrisville NC
Scott C. Mayer - Robbinsville NJ
Robert E. McDevitt - Somerset NJ
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 3117
US Classification:

514596, 564 48, 562457, 560 19, 560 43, 514572, 514485, 514476
Abstract:

This invention provides compounds of formula I having the structure wherein: B, D, C, and R as defined herein.

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia
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US Patent:

7008636, Mar 7, 2006
Filed:

May 11, 2004
Appl. No.:

10/843026
Inventors:

John A. Butera - Clarksburg NJ, US
Craig E. Caufield - New York NY, US
Russell F. Graceffa - Hampton NH, US
Alexander Greenfield - Princeton Junction NJ, US
Eric G. Gundersen - Plainsboro NJ, US
Lisa Marie Havran - Bordentown NJ, US
Alan H. Katz - Lawrenceville NJ, US
Joseph R. Lennox - Morrisville NC, US
Scott C. Mayer - Robbinsville NJ, US
Robert E. McDevitt - Somerset NJ, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/343
A61K 31/19
C07D 307/78
C07C 53/134
US Classification:

424433, 549471, 562512, 562587, 5483351, 548469, 548470, 546339, 514469, 514416, 514415, 514396, 514354, 514571
Abstract:

This invention provides compounds of Formula I having the structure or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

Pyrimidoindolones And Methods For Using Same
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US Patent:

7256198, Aug 14, 2007
Filed:

Feb 18, 2005
Appl. No.:

11/061144
Inventors:

Paul Jeffrey Dollings - Newtown PA, US
Arlene Joan Dietrich - Delran NJ, US
Lisa Marie Havran - Florence NJ, US
Donna Mary Huryn - Allentown NJ, US
Albert Jean Robichaud - Ringoes NJ, US
Boyd Lynn Harrison - Princeton Junction NJ, US
Wayne Everett Childers - New Hope PA, US
Alexander A. Greenfield - West Windsor NJ, US
James Jacob Bicksler - Titusville NJ, US
Vasilios Marathias - Pennington NJ, US
Assignee:

Wyeth - Madison NJ
International Classification:

A01N 43/54
A61K 31/505
C07D 239/00
C07D 239/70
C07D 471/00
C07D 487/00
US Classification:

514267, 544252
Abstract:

Novel pyrimidoindolone compounds are disclosed. Methods of using the pyrimidoindolone compounds and compositions containing the compounds in the treatment and/or prevention of disease and other conditions related to inflammation, neurodegeneration, osteoarthritis and apoptosis are also disclosed.

Substituted Indole Oximes
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US Patent:

7342039, Mar 11, 2008
Filed:

Sep 23, 2004
Appl. No.:

10/947846
Inventors:

Lisa Marie Havran - Florence NJ, US
John Anthony Butera - Clarksburg NJ, US
Hassan Mahmoud Elokdah - Yardley PA, US
Douglas John Jenkins - Collegeville PA, US
Eric Gould Gundersen - Royersford PA, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/404
C07D 209/04
US Classification:

514415, 548469, 548490, 548491, 548146, 548182, 548215, 548229, 548125, 548129, 548132, 548250, 548252, 548240, 548243, 5482622, 5483647, 514361, 514364, 514372, 514381
Abstract:

The present invention relates to substituted indole oximes and methods of using them.

Substituted Aryloximes
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US Patent:

7420083, Sep 2, 2008
Filed:

Sep 23, 2004
Appl. No.:

10/948611
Inventors:

Lisa Marie Havran - Florence NJ, US
John Anthony Butera - Clarksburg NJ, US
Hassan Mahmoud Elokdah - Yardley PA, US
Douglas John Jenkins - Collegeville PA, US
Eric Gould Gundersen - Royersford PA, US
Assignee:

Wyeth - Madison NJ
International Classification:

C07C 63/06
A61K 31/19
US Classification:

562440, 514568, 514570
Abstract:

The present invention relates to substituted aryl oximes and methods of using them.

Piperazine-Piperidine Antagonists And Agonists Of The 5-Ht Receptor
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US Patent:

7671056, Mar 2, 2010
Filed:

Jun 9, 2006
Appl. No.:

11/450942
Inventors:

Magda Asselin - Mahwah NJ, US
George Theodore Grosu - Pearl River NY, US
Annmarie Louise Sabb - Pennington NJ, US
Wayne Everett Childers - New Hope PA, US
Lisa Marie Havran - Florence NJ, US
Zhongqi Shen - Plainsboro NJ, US
James Jacob Bicksler - Titusville NJ, US
Dan Chaekoo Chong - Plainsboro NJ, US
Assignee:

Wyeth LLC - Madison NJ
International Classification:

A61K 31/496
C07D 401/14
C07D 405/14
C07D 409/14
C07D 413/14
US Classification:

51425306, 51425307, 51425308, 51425309, 5142531, 51425311, 544363, 544360, 544364
Abstract:

The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agonists. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction. The invention relates to compounds and pharmaceutically acceptable salts of formula (I′):.

Substituted Benzofuran Oximes
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US Patent:

20050215626, Sep 29, 2005
Filed:

Sep 23, 2004
Appl. No.:

10/947930
Inventors:

Lisa Havran - Florence NJ, US
John Butera - Clarksburg NJ, US
Hassan Elokdah - Yardley PA, US
Douglas Jenkins - Collegeville PA, US
Eric Gundersen - Rogersford PA, US
Assignee:

WYETH - Madison NJ
International Classification:

A61K031/343
C07D307/78
US Classification:

514469000, 549467000
Abstract:

The present invention relates to substituted benzofuran oximes and methods of using them.